Results 51 to 60 of about 75,138 (262)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Electrical phase angle as a new method to measure fish condition [PDF]

open access: yes, 2009
In this study, phase angle (the ratio of resistance and reactance of tissue to applied electrical current) is presented as a possible new method to measure fish condition.
Cox, Keith W., Heintz, Ron
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

THE ESTIMATION OF THE TIME SINCE DEATH

open access: yesZdravniški Vestnik, 2002
Background. The retrograde estimation of the time since death is still unsuccessfully solved problem in forensic medicine. The registration of the time of death is the principle task of every coroner.
Peter Kadiš
doaj  

Postmortem Temporal Changes in Liver and Spleen Stiffness: Evaluation with Shear Wave Elastography in a Rat Model

open access: yesDiagnostics
Background/Objectives: Postmortem changes in tissue stiffness and organ morphology are critical for forensic medicine and pathology. Shear wave elastography (SWE) has emerged as a non-invasive tool to assess tissue stiffness, yet its potential for ...
Ismail Taskent   +6 more
doaj   +1 more source

Selective time-dependent changes in activity and cell-specific gene expression in human postmortem brain

open access: yesScientific Reports, 2021
As a means to understand human neuropsychiatric disorders from human brain samples, we compared the transcription patterns and histological features of postmortem brain to fresh human neocortex isolated immediately following surgical removal. Compared to
Fabien Dachet   +9 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Gambaran Makroskopik Dan Mikroskopik Otot Skelet Pada Hewan Coba Postmortem [PDF]

open access: yes, 2016
: To make pathologists and law personnel aware of the importance of postmortem interval, published studies have reported a lot of methods for estimation of postmortem interval estimation of the remains.
Nelwan, G. B. (Gabriella)   +2 more
core  

Succession of oral microbiota community as a tool to estimate postmortem interval

open access: yesScientific Reports, 2019
The establishment of postmortem interval is one of the most important aspects of forensic expertise. Microbes may provide a novel way to estimate the postmortem intervals in order to avoid many of these limitations.
Kaikai Dong   +7 more
doaj   +1 more source

Changes in Autophagy during Postmortem Aging of Beef [PDF]

open access: yesShipin Kexue
s: In this study, the changes in autophagy and its relationship with beef quality during 14 days of postmortem aging were investigated. In terms of meat color, the L* value increased with aging time, and the a* and b* values increased first and then ...
LI Ye, LU Wenjie, WANG Hairong, YANG Xiaoyin, LIU Yunge, LIANG Rongrong, MAO Yanwei, ZHANG Yimin, ZHU Lixian
doaj   +1 more source

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