Results 121 to 130 of about 2,621,362 (287)

Does expecting more pain make it more intense? Factors associated with the first week pain trajectories after breast cancer surgery [PDF]

, 2017
The aim of this study was to identify clinical risk factors for unfavorable pain trajectories after breast cancer surgery, to better understand the association between pain expectation, psychological distress, and acute postoperative pain.
Althaus, Andersen, Andersen, Apkarian, Atlas, Beck, Boersma, Brodner, Brown, Bruce, Bruce, Burns, Cabodi, Caumo, Chapman, Colloca, Eccleston, Gerbershagen, Gramke, Hickey, Hoofwijk, Huber, Ip, Jemal, Katz, Kaunisto, Keogh, Kirsch, Koyama, Logan, Masselin-Dubois, Meretoja, Montgomery, Montgomery, Montgomery, Montgomery, Morley, Pan, Pan, Pavlin, Pinto, Schubart, Sharpe, Sipila, Sommer, Tracey, Vlaeyen   +46 more
core   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Benefits of thoracic epidural analgesia in patients undergoing an open posterior component separation for abdominal herniorrhaphy [PDF]

, 2017
INTRODUCTION: The implementation of open posterior component separation (PCS) surgery has led to improved outcomes for complex hernias. While the PCS technique has been shown to decrease recurrence rates, and provide a feasible option to repair hernias ...
Sellers, Austin
core   +1 more source

Preoperative Patient Expectations of Postoperative Pain Are Associated with Moderate to Severe Acute Pain After VATS

Pain medicine (Malden, Mass.), 2018
OBJECTIVE The goal of this post hoc analysis of subjects from a prospective observational study was to identify the predictors of patients developing moderate to severe acute pain (mean numerical rating scale [NRS] ≥4, 0-10) during the first three days ...
E. Bayman, K. Parekh, J. Keech, Nyle Larson, M. V. Vander Weg, T. Brennan   +5 more
semanticscholar   +1 more source

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

Advanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan, Han‐Wen Gu, Yan‐Bo Zhou, Sophie Ma, Daqing Ma, Pan‐Miao Liu, Jian‐Jun Yang   +6 more
wiley   +1 more source

Caregivers’ role regarding managing postoperative pain of hospitalised children (0–3 years)

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: Acute postoperative pain is a common surgical symptom affecting 40% - 80% of patients. Postoperative pain produces much distress in children. Effective postoperative pain management is a human right. Various stakeholders, including caregivers,
Sylvia Oger Ofosu-Dwamena, Carin Maree, Seugnette Rossouw, Varshika Bhana-Pema   +3 more
doaj   +1 more source

Effect of Perioperative Gabapentin on Postoperative Pain Resolution and Opioid Cessation in a Mixed Surgical Cohort: A Randomized Clinical Trial

JAMA Surgery, 2017
Importance Guidelines recommend using gabapentin to decrease postoperative pain and opioid use, but significant variation exists in clinical practice.
Jennifer M. Hah, S. Mackey, P. Schmidt, R. McCue, K. Humphreys, J. Trafton, B. Efron, D. Clay, Y. Sharifzadeh, G. Ruchelli, S. Goodman, J. Huddleston, W. Maloney, F. Dirbas, J. Shrager, J. Costouros, Catherine Curtin, Ian R Carroll   +17 more
semanticscholar   +1 more source

Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The impact of topography on the secretome of adipose‐derived stem cells (ADSCs) has the potential for promoting tendon regeneration. The secretome generated from ADSCs on aligned structure has a potent effect in promoting cell migration, proliferation, tenogenic differentiation, macrophage M2 polarization, and tendon mechanical function recovery ...
Qiuzi Long, Chuanquan Liu, Haotian Zheng, Mingyue Wang, Hanmei Liu, Yue Liu, Zhicheng Cao, Yuzhi Sun, Qingyun Mo, Ludvig J. Backman, Jialin Zhu, Lizhi Hu, Jinlong Huang, Wei Zhang, Jialin Chen   +14 more
wiley   +1 more source

Comparison of different pain management strategies during the perioperative period of esophageal squamous cell carcinoma: a retrospective cohort study

Perioperative Medicine
Objective This retrospective cohort study aims to evaluate and compare different postoperative pain management strategies for esophageal squamous cell carcinoma (ESCC), in order to provide scientific evidence for clinical practice and decision-making ...
Yan Ma, Haiyan Wu, Xinqi Wei, Ying Yang, Zhiyun Xu, Yunyun Chen   +5 more
doaj   +1 more source

Manipulation of Oxygen Tension in Damaged Regions via Hypoxia‐Induced IPN Hydrogel Microspheres for Intervertebral Disc Regeneration

Advanced Science, EarlyView.
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou, Zhendong Lv, Zehao Chen, Yiming Xu, Chao Lin, Li Liu, Hao Chen, Bing Niu, Wenguo Cui, Yuhui Zhang   +9 more
wiley   +1 more source