Results 61 to 70 of about 3,204,314 (308)

The Relationship of Postoperative Pain and Opioid Consumption to Postoperative Delirium After Spine Surgery

Journal of Pain Research, 2023
Ryan Sica,1 Jenna M Wilson,1 Erin J Kim,1 Deborah J Culley,1,2 Samantha M Meints,1 Kristin L Schreiber1 1Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; 2Department of
Sica R, Wilson JM, Kim EJ, Culley DJ, Meints SM, Schreiber KL   +5 more
doaj  

PROSPECT guideline for rotator cuff repair surgery: systematic review and procedure‐specific postoperative pain management recommendations

Anaesthesia, 2019
Rotator cuff repair can be associated with significant and difficult to treat postoperative pain. We aimed to evaluate the available literature and develop recommendations for optimal pain management after rotator cuff repair.
O. Toma, B. Persoons, E. Pogatzki-Zahn, M. Van de Velde, G. Joshi, S H F N A P H J A E P Schug Kehlet Bonnet Rawal Delbos Lavand'homme Belo, S. Schug, H. Kehlet, F. Bonnet, N. Rawal, A. Delbos, P. Lavand'homme, H. Beloeil, J. Raeder, A. Sauter, E. Albrecht, P. Lirk   +16 more
semanticscholar   +1 more source

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.

Anesthesiology, 2020
BACKGROUND Widely used for acute pain management, the clinical benefit from perioperative use of gabapentinoids is uncertain. The aim of this systematic review was to assess the analgesic effect and adverse events with the perioperative use of ...
Michael Verret, F. Lauzier, R. Zarychanski, Caroline Perron, Xavier Savard, A. Pinard, G. Leblanc, Marie-Joëlle Cossi, X. Neveu, A. Turgeon, A. Mcauley, A. Flexman, A. Denault, A. Jerath, Christopher Prabhakar, C. McCartney, C. Sawchuk, Cynthia H. Yarnold, D. Boyle, D. Mazer, David Roach, D. Tran, D. McKeen, D. Yee, D. Wijeysundera, E. Belley‐Cote, E. Jacobsohn, É. de Médicis, F. Carrier, G. Hare, G. Bryson, H. Grocott, Homer Yang, Jason A. McVicar, Jennifer O'Brien, J. Spence, Jim Kim, J. Murkin, Jonathan J. Gamble, K. Sparrow, Kimberley Wong, S. McCluskey, Michael Bautista, M. Law, Michael Schmidt, Nicola Y Edwards, P. Choi, P. Richebé, P. Beaulieu, R. Sondekoppam, R. Arellano, R. Dhawan, Richard Hall, Ron Ree, R. George, R. Chun, S. Brudney, S. Kowalski, S. Syed, S. Sidhu, Tarit Saha, Thomas Mutter, V. Uppal   +62 more
semanticscholar   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

Revision of expert panel's guidelines on postoperative pain management.

Anaesthesia Critical Care & Pain Medicine, 2019
The French Society of Anaesthesia and Intensive Care Medicine (SFAR) published experts' guidelines on the care of postoperative pain. This was an update of the 2008 guidelines.
F. Aubrun, K. Nouette-Gaulain, D. Fletcher, A. Belbachir, H. Beloeil, M. Carles, P. Cuvillon, C. Dadure, G. Lebuffe, E. Marret, V. Martinez, M. Olivier, N. Sabourdin, P. Zetlaoui   +13 more
semanticscholar   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Percutaneous auricular neuromodulation to treat pain after ambulatory breast surgery: A randomized, double-masked, sham-controlled pilot study

Canadian Journal of Pain
Introduction Percutaneous auricular neuromodulation involves implanting electrodes around the ear and administering an electric current. A device is currently available that is cleared to treat symptoms from opioid withdrawal, and multiple reports ...
Brian M. Ilfeld, Wendy B. Abramson, Engy T. Said, Jacklynn F. Sztain, John J. Finneran, Jonna L. Griggs, Baharin Abdullah, Evan J. Jensen, Adam Schaar, Anne M. Wallace   +9 more
doaj   +1 more source

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND The management of postoperative pain and recovery is still unsatisfactory in a number of cases in clinical practice. Opioids used for postoperative analgesia are frequently associated with adverse effects, including nausea and constipation ...
S. Weibel, Y. Jelting, N. Pace, A. Helf, L. Eberhart, K. Hahnenkamp, M. Hollmann, D. Poepping, A. Schnabel, P. Kranke   +9 more
semanticscholar   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source