Results 61 to 70 of about 585,226 (323)

The association between maternal vitamin D deficiency and postpartum hemorrhage and uterine atony

Acta Obstetricia et Gynecologica Scandinavica
Introduction Postpartum hemorrhage is the leading cause of maternal morbidity and mortality worldwide. There are several known risk factors for postpartum hemorrhage related to pregnancy and delivery, but less evidence of predisposing factors.
Anna Sörsjö Stevenazzi, Sofia Pihl, Marie Blomberg, Daniel Axelsson   +3 more
doaj   +1 more source

Design of a postpartum hemorrhage and transfusion risk calculator

Heliyon, 2023
Background: Postpartum hemorrhage is the major cause of maternal deaths due to childbirth and also responsible for maternal morbidity. Objectives: In this study we set out to look the incidence of postpartum hemorrhage in our population, to identify the ...
Lissette A. Gonzalez Carrillo, Cristina Ruiz de Aguiar, Jesús Martin Muriel, Miguel A. Rodriguez Zambrano   +3 more
doaj  

Platelet count and indices as postpartum hemorrhage risk factors: a retrospective cohort study

Journal of Thrombosis and Haemostasis, 2021
Severe postpartum hemorrhage (SPPH) is the leading cause of maternal mortality and morbidity worldwide. Platelet anomalies frequently occur during pregnancy. However, their role in the etiology of SPPH is largely unknown.
Wobke E M van Dijk, Jelle S. Nijdam, S. Haitjema, Mark C.H. de Groot, A. Huisman, M. Punt, Annemiek C. C. Evers, R. Schutgens, A. Lely, K. V. van Galen   +9 more
semanticscholar   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Anemia during pregnancy and its influence on postpartum hemorrhage

Medisains
Background: Up to 50% of pregnant women in low-income and middle-income countries are affected by anemia, and 30.43% of maternal deaths in Indonesia occur during the postpartum period.
Syamsuriyati Syamsuriyati, Rika Handayani, Sunartono Suhartono, Sutriani Syarif, Nurhidayat Triananinsi   +4 more
doaj   +1 more source

Quantification of Blood Loss Improves Detection of Postpartum Hemorrhage and Accuracy of Postpartum Hemorrhage Rates: A Retrospective Cohort Study

Cureus, 2021
Objective To evaluate the ability of estimated blood loss (EBL) and quantitative blood loss (QBL) to predict the need for blood transfusion in postpartum patients.
Colleen Blosser, Alisha M. Smith, Aaron T. Poole   +2 more
semanticscholar   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

A ruptured vulvar labial artery pseudoaneurysm causes a secondary postpartum hemorrhage: A case report

Case Reports in Women's Health, 2020
Background: Postpartum hemorrhage is the most common cause of maternal morbidity in the United States. However, secondary postpartum hemorrhage is rare and includes pseudoaneurysms, which represent only 3.3% of all cases of secondary postpartum ...
Marie-Claire Leaf, Luke Schmidt, Tasha Serna-Gallegos, Felicia Lane   +3 more
doaj