Results 141 to 150 of about 9,516,972 (308)

Metal‐Mediated Protein Engineering within Live Cells

open access: yesChemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.
This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley   +1 more source

A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome

open access: yesAutism Research, EarlyView.
ABSTRACT Although there are as many as 40 preclinical models of the neurodevelopmental disorder Phelan McDermid syndrome (PMS, or 22q13.3 deletion syndrome), detailed phenotypic analyses to compare the effects of different pathogenic variants and inform treatment design are lacking.
Vic Lin   +7 more
wiley   +1 more source

GDF10 Regulates Iron‐Dependent Lipid Oxidation in Colorectal Cancer Cells Through Interaction With IGF2

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Background: This study aims to identify genes with a high likelihood of genetic variation, significant expression differences, and prognostic implications in colorectal cancer (CRC) patients. The research also seeks to investigate the role and mechanisms of key genes in CRC through the analysis of health information data and a combination of ...
Kaobin Ouyang   +3 more
wiley   +1 more source

Mitochondrial Microproteins: Emerging Regulators in Neurodevelopment and Neurodegeneration

open access: yesBioEssays, EarlyView.
Mitochondrial microproteins have emerged as critical regulators of mitochondrial function. Neurons are highly dependent on mitochondria to sustain their function. Mitochondrial microproteins can be deregulated and can contribute to the pathogenesis of neurodegenerative disorders. Mitochondrial microproteins are involved in neuronal development. However,
Nada Borghol   +2 more
wiley   +1 more source

A neuromorphic processor with on-chip learning for beyond-CMOS device integration. [PDF]

open access: yesNat Commun
Greatorex H   +12 more
europepmc   +1 more source

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