Conformational Rearrangement of Fission DSPs
Assembly properties of fission DSPs. Fission DSPs exist in a dynamic equilibrium of oligomer states in the cytosol, where they must be activated by partner proteins or lipid to induce assembly, and upon GTP hydrolysis, constriction. ABSTRACT Dynamin superfamily proteins (DSPs) are large GTPases that play crucial roles in membrane remodeling processes ...
Anelise N. Hutson+2 more
wiley +1 more source
Spike Timing-Dependent Plasticity and Random Inputs Shape Interspike Interval Regularity of Model STN Neurons. [PDF]
Thieu T, Melnik R.
europepmc +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Impact of Dendritic Spine Loss on Excitability of Hippocampal CA1 Pyramidal Neurons: A Computational Study of Early Alzheimer Disease. [PDF]
Tian C, Reyes I, Johnson A, Masurkar AV.
europepmc +1 more source
The role of auditory sensory input during functional pre- and postsynaptic maturation of the calyx of Held synapse. [PDF]
Erazo Fischer, E.
core +1 more source
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti+4 more
wiley +1 more source
Theoretical analysis of low power optogenetic control of synaptic plasticity with subcellular expression of CapChR2 at postsynaptic spine. [PDF]
Dixit N, Pyari G, Bansal H, Roy S.
europepmc +1 more source
Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse.
R. Llinás, I. Z. Steinberg, K. Walton
semanticscholar +1 more source