Results 11 to 20 of about 156,710 (324)
Phencyclidine (PCP) blocks glutamate‐activated postsynaptic currents [PDF]
Phencyclidine Glutamate receptor Locust Neuromuscular transmission Excitatory postsynaptic current Channel blacker
Idriss, M., Albuquerque, E.X.
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Kappa Opioid Inhibition of Somatodendritic Dopamine Inhibitory Postsynaptic Currents [PDF]
In the midbrain, dopamine neurons can release dopamine somatodendritically. This results in an inhibitory postsynaptic current (IPSC) within adjacent dopamine cells that occurs by the activation of inhibitory D2autoreceptors. Kappa, but not mu/delta, opioid receptors inhibit this IPSC.
Christopher Ford +2 more
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Estimating Transmitter Release Rates from Postsynaptic Current Fluctuations [PDF]
A method is presented that allows one to estimate transmitter release rates from fluctuations of postsynaptic current records under conditions of stationary or slowly varying release. For experimental applications, we used the calyx of Held, a glutamatergic synapse, in which “residual current,” i.e., current attributable to residual glutamate in the ...
Neher, E., Sakaba, T.
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Voltage sensitivity of NMDA-receptor mediated postsynaptic currents [PDF]
Patch-clamp techniques were used to record pharmacologically-isolated N-methyl-D-aspartate-mediated excitatory postsynaptic currents (NMDA-EPSCs) from dentate granule cells in thin rat hippocampal slices. Membrane voltage modulated these EPSCs in two ways.
Konnerth, A. +3 more
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Contribution of Membrane Lipids to Postsynaptic Protein Organization
The precise subsynaptic organization of proteins at the postsynaptic membrane controls synaptic transmission. In particular, postsynaptic receptor complexes are concentrated in distinct membrane nanodomains to optimize synaptic signaling.
Manon Westra +2 more
doaj +1 more source
Mutations in synaptic NMDA receptors (NMDARs) are associated with epilepsy and neurodevelopmental disorders. The effects of several such mutations have been investigated in recombinantly-expressed NMDARs under conditions of steady-state activation.
Xiumin Chen +3 more
doaj +1 more source
NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix +3 more
core +1 more source
To understand the information encoded in a connection between the neurons, postsynaptic current (PSC) has been widely measured as a primary index of synaptic strength in the field of neurophysiology.
Yong Gyu Kim +2 more
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Enhancement of synchronization in a hybrid neural circuit by spike timing dependent plasticity [PDF]
Synchronization of neural activity is fundamental for many functions of the brain. We demonstrate that spike-timing dependent plasticity (STDP) enhances synchronization (entrainment) in a hybrid circuit composed of a spike generator, a dynamic clamp ...
Abarbanel, Henry D I +4 more
core +2 more sources
Neurons in the central nucleus of the inferior colliculus (ICC) receive ascending inputs from the ipsilateral and contralateral auditory pathway.
Jinxing Wei +5 more
doaj +1 more source

