Results 11 to 20 of about 156,710 (324)

Phencyclidine (PCP) blocks glutamate‐activated postsynaptic currents [PDF]

open access: yesFEBS Letters, 1985
Phencyclidine Glutamate receptor Locust Neuromuscular transmission Excitatory postsynaptic current Channel blacker
Idriss, M., Albuquerque, E.X.
openaire   +2 more sources

Kappa Opioid Inhibition of Somatodendritic Dopamine Inhibitory Postsynaptic Currents [PDF]

open access: greenJournal of Neurophysiology, 2006
In the midbrain, dopamine neurons can release dopamine somatodendritically. This results in an inhibitory postsynaptic current (IPSC) within adjacent dopamine cells that occurs by the activation of inhibitory D2autoreceptors. Kappa, but not mu/delta, opioid receptors inhibit this IPSC.
Christopher Ford   +2 more
openalex   +4 more sources

Estimating Transmitter Release Rates from Postsynaptic Current Fluctuations [PDF]

open access: yesThe Journal of Neuroscience, 2001
A method is presented that allows one to estimate transmitter release rates from fluctuations of postsynaptic current records under conditions of stationary or slowly varying release. For experimental applications, we used the calyx of Held, a glutamatergic synapse, in which “residual current,” i.e., current attributable to residual glutamate in the ...
Neher, E., Sakaba, T.
openaire   +4 more sources

Voltage sensitivity of NMDA-receptor mediated postsynaptic currents [PDF]

open access: yesExperimental Brain Research, 1990
Patch-clamp techniques were used to record pharmacologically-isolated N-methyl-D-aspartate-mediated excitatory postsynaptic currents (NMDA-EPSCs) from dentate granule cells in thin rat hippocampal slices. Membrane voltage modulated these EPSCs in two ways.
Konnerth, A.   +3 more
openaire   +4 more sources

Contribution of Membrane Lipids to Postsynaptic Protein Organization

open access: yesFrontiers in Synaptic Neuroscience, 2021
The precise subsynaptic organization of proteins at the postsynaptic membrane controls synaptic transmission. In particular, postsynaptic receptor complexes are concentrated in distinct membrane nanodomains to optimize synaptic signaling.
Manon Westra   +2 more
doaj   +1 more source

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors

open access: yesNeurobiology of Disease, 2020
Mutations in synaptic NMDA receptors (NMDARs) are associated with epilepsy and neurodevelopmental disorders. The effects of several such mutations have been investigated in recombinantly-expressed NMDARs under conditions of steady-state activation.
Xiumin Chen   +3 more
doaj   +1 more source

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

open access: yes, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix   +3 more
core   +1 more source

Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events

open access: yesMolecular Brain, 2021
To understand the information encoded in a connection between the neurons, postsynaptic current (PSC) has been widely measured as a primary index of synaptic strength in the field of neurophysiology.
Yong Gyu Kim   +2 more
doaj   +1 more source

Enhancement of synchronization in a hybrid neural circuit by spike timing dependent plasticity [PDF]

open access: yes, 2003
Synchronization of neural activity is fundamental for many functions of the brain. We demonstrate that spike-timing dependent plasticity (STDP) enhances synchronization (entrainment) in a hybrid circuit composed of a spike generator, a dynamic clamp ...
Abarbanel, Henry D I   +4 more
core   +2 more sources

Selectivity of Monaural Synaptic Inputs Underlying Binaural Auditory Information Integration in the Central Nucleus of Inferior Colliculus

open access: yesFrontiers in Cellular Neuroscience, 2018
Neurons in the central nucleus of the inferior colliculus (ICC) receive ascending inputs from the ipsilateral and contralateral auditory pathway.
Jinxing Wei   +5 more
doaj   +1 more source

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