Results 1 to 10 of about 142,409 (303)
Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex [PDF]
Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects.
Jia Hui Wong, Faruque Reza, Sangu Muthuraju, Huei Gau Chuang, Jingli Zhang, Mohd Harizal Senik, Siti Rafidah Yusof, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Nor Hadiani Ismail, Jafri Malin Abdullah
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Imperfect space clamp permits electrotonic interactions between inhibitory and excitatory synaptic conductances, distorting voltage clamp recordings. [PDF]
The voltage clamp technique is frequently used to examine the strength and composition of synaptic input to neurons. Even accounting for imperfect voltage control of the entire cell membrane ("space clamp"), it is often assumed that currents measured at ...
Alon Poleg-Polsky, Jeffrey S Diamond
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Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus
Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
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IntroductionN-methyl-D-aspartate receptor (NMDAR) is one of the main receptor of the excitatory neurotransmitter glutamate in the brain, which is the key determinant of the excitatory/inhibitory balance of neural network.
Teng Zhao +7 more
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Probabilistic Fluorescence-Based Synapse Detection [PDF]
Brain function results from communication between neurons connected by complex synaptic networks. Synapses are themselves highly complex and diverse signaling machines, containing protein products of hundreds of different genes, some in hundreds of ...
Aguerrebere, Cecilia +7 more
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Binge‐like exposure to ethanol during the brain growth spurt triggers apoptotic neurodegeneration in multiple brain regions, including the retrosplenial cortex, a brain region that is part of the hippocampal‐diencephalic‐cingulate memory network. This is
Clark W. Bird, Carlos F. Valenzuela
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In the cerebellar cortex, molecular layer interneurons use chemical and electrical synapses to form subnetworks that fine-tune the spiking output of the cerebellum.
Andreas Hoehne +2 more
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Hyperpolarization following activation of K+ channels by excitatory postsynaptic potentials [PDF]
We have postulated that an excitatory postsynaptic potential (e.p.s.p.) may open voltage-sensitive K+ ('M') channels, in an appropriate depolarizing range, and that this could alter the e.p.s.p. waveform. Consequently, the fast e.p.s.p. in neurones of sympathetic ganglia, elicited by a nicotinic action of acetylcholine (ACh), could be followed by a ...
Tosaka, Tsuneo +3 more
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Synaptic plasticity is a critical process that regulates neuronal activity by allowing neurons to adjust their synaptic strength in response to changes in activity.
Caitlyn A. Chapman +2 more
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Recent studies have demonstrated an important role of the pro-inflammatory cytokine interferon-γ in neuropathic pain. Interferon-γ is upregulated in the lumbar spinal cord of nerve-injured rodents and intrathecal injection of interferon-γ has been shown ...
Gerda Reischer +2 more
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