Results 1 to 10 of about 111,000 (118)
XE991 Reverses Enhanced Short-Term Plasticity in Rat Epileptic CA1. [PDF]
Brain SciBackground/Objectives: Recent evidence has suggested a transcriptional reduction in Kv7 potassium channels in the CA1 area of acquired experimental epilepsy, but presynaptic Kv7 channels might be spared.
Schnell E +3 more
europepmc +2 more sources
Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex [PDF]
Journal of Integrative Neuroscience, 2020 Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects.
Jia Hui Wong, Faruque Reza, Sangu Muthuraju, Huei Gau Chuang, Jingli Zhang, Mohd Harizal Senik, Siti Rafidah Yusof, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Nor Hadiani Ismail, Jafri Malin Abdullah
doaj +1 more source
Imperfect space clamp permits electrotonic interactions between inhibitory and excitatory synaptic conductances, distorting voltage clamp recordings. [PDF]
PLoS ONE, 2011 The voltage clamp technique is frequently used to examine the strength and composition of synaptic input to neurons. Even accounting for imperfect voltage control of the entire cell membrane ("space clamp"), it is often assumed that currents measured at ...
Alon Poleg-Polsky, Jeffrey S Diamond
doaj +1 more source
Cortical PV and VIP interneurons similarly influence SST neuron output despite distinct unitary properties. [PDF]
Commun BiolSomatostatin (SST) expressing cells are powerful inhibitors of excitatory pyramidal neurons. It has been shown that SST cells are targeted by other inhibitory interneurons, namely parvalbumin- (PV) and vasoactive intestinal polypeptide- (VIP) expressing ...
Preuss F, Möck M, Witte M, Staiger JF.
europepmc +2 more sources
Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus
Brain Stimulation, 2022 Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
doaj +1 more source
Frontiers in Neuroscience, 2023 IntroductionN-methyl-D-aspartate receptor (NMDAR) is one of the main receptor of the excitatory neurotransmitter glutamate in the brain, which is the key determinant of the excitatory/inhibitory balance of neural network.
Teng Zhao +7 more
doaj +1 more source
Neuropsychopharmacology Reports, 2023 Binge‐like exposure to ethanol during the brain growth spurt triggers apoptotic neurodegeneration in multiple brain regions, including the retrosplenial cortex, a brain region that is part of the hippocampal‐diencephalic‐cingulate memory network. This is
Clark W. Bird, Carlos F. Valenzuela
doaj +1 more source
eLife, 2020 In the cerebellar cortex, molecular layer interneurons use chemical and electrical synapses to form subnetworks that fine-tune the spiking output of the cerebellum.
Andreas Hoehne +2 more
doaj +1 more source
Frontiers in Synaptic Neuroscience, 2022 Synaptic plasticity is a critical process that regulates neuronal activity by allowing neurons to adjust their synaptic strength in response to changes in activity.
Caitlyn A. Chapman +2 more
doaj +1 more source
Molecular Pain, 2020 Recent studies have demonstrated an important role of the pro-inflammatory cytokine interferon-γ in neuropathic pain. Interferon-γ is upregulated in the lumbar spinal cord of nerve-injured rodents and intrathecal injection of interferon-γ has been shown ...
Gerda Reischer +2 more
doaj +1 more source