Results 201 to 210 of about 9,516,972 (308)

Towards a quantum synapse for quantum sensing. [PDF]

Sci Rep
Pau LF.
europepmc   +1 more source

Disease‐Modifying Trials in Treated Parkinson's Disease: “Stable Treated” Does Not Equate with Biological Stability

Movement Disorders, EarlyView.
Abstract Traditionally, clinical trials of putative disease‐modifying therapies in Parkinson's disease have enrolled untreated patients at the earliest clinical stages of their disease. Due to a number of challenges inherent with this approach, there has been a recent move to a different study design, enrolling patients who are already taking “stable ...
M. Maral Mouradian, A. Jon Stoessl, Anthony E. Lang   +2 more
wiley   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

The effects and mechanisms of stem cells and exosomes on neurological function protection and recovery after ischemic stroke

Neuroprotection, EarlyView.
Effect and mechanism of stem cells and exosomes therapy in ischemic stroke. The effect and mechanism include protection of neuron and glial cells, repairment of nerve vascular unit, reduction of inflammation response, restoration of white matter integrity, reconstruction of neural circuit, replacement of neurons and glial cells, and anti‐ferroptosis ...
Weihong Du, Yuxian He, Liangchen Li, Xinchun Jin, Panpan Geng   +4 more
wiley   +1 more source

Impacts of perinatal nicotine exposure on nicotinic acetylcholine receptor expression and glutamatergic synaptic transmission in the mouse auditory brainstem. [PDF]

J Physiol
Wollet M, Hernandez A, Nip K, Ginsburg B, Pugh JR, Kim JH.   +5 more
europepmc   +1 more source

Neuroprotective Efficacy of Microwave‐Assisted Synthetized 2‐(5‐Cyclopropyl‐6‐Thioxo‐1,3,5‐Thiadiazinan‐3‐Yl) Acetic Acid in Mitigating Cognitive Deficits in Pentylenetetrazole‐Induced Mice Model

ChemistryOpen, EarlyView.
Microwave synthesis yielded 2‐(5‐cyclopropyl‐6‐thioxo‐1,3,5‐thiadiazinan‐3‐yl)acetic acid, confirmed by infrared, nuclear magnetic resonance, and electron ionization mass spectrometry. In a pentylenetetrazole‐induced epilepsy model, it countered oxidative stress by boosting antioxidant enzymes (catalase, peroxidase, superoxide dismutase, glutathione ...
Tahir Iqbal, Murad A. Mubaraki, Ahmad Khushal, Amena Arif, Fozia Fozia, Shahid Ali Shah, Ijaz Ahmad, Rasool Khan, Najeeb Ur Rehman, Ziaullah Ziaullah   +9 more
wiley   +1 more source

Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A

Andrew G. Koesters, Mark M. Rich, Kathrin L. Engisch   +2 more
openalex   +2 more sources

Calcium signaling in postsynaptic mitochondria: mechanisms, dynamics, and role in ATP production. [PDF]

Front Mol Neurosci
Feofilaktova T, Kushnireva L, Segal M, Korkotian E.   +3 more
europepmc   +1 more source

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Whole-body connectome of a segmented annelid larva. [PDF]

Elife
Verasztó C, Jasek S, Gühmann M, Bezares-Calderón LA, Williams EA, Shahidi R, Jékely G.   +6 more
europepmc   +1 more source