Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley +1 more source
Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex. [PDF]
Glausier JR+8 more
europepmc +1 more source
Mechanisms that regulate the C1-C2B mutual inhibition control functional switch of UNC-13. [PDF]
Liu H+11 more
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Circularly Polarized Light-Responsive Flexible Synapses Based on Supramolecular <i>n</i>-Type Chiral Organic Single Crystal/<i>p</i>-Type Polymer Heterojunctions. [PDF]
Kim B, Ahn J, Gao K, Shang X, Oh JH.
europepmc +1 more source
Differentiated SH-SY5Y Cells Exhibit Neuronal Features but Lack Synaptic Maturity
Leuenberger J+4 more
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A ventral pallidal glutamatergic aversive network encodes abstinence from and reexposure to cocaine. [PDF]
Levi LA, Inbar K, Tseiger E, Kupchik YM.
europepmc +1 more source
Accelerated signal propagation speed in human neocortical dendrites. [PDF]
Oláh G+9 more
europepmc +1 more source
Acute stress causes sex-specific changes to ventral subiculum synapses, circuitry, and anxiety-like behavior. [PDF]
Miller CN, Li Y, Beier KT, Aoto J.
europepmc +1 more source