Results 261 to 270 of about 9,516,972 (308)
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Postsynaptically different inhibitory postsynaptic currents in Cajal–Retzius cells in the developing neocortex

NeuroReport, 2008
Fast and slowly rising inhibitory postsynaptic currents (IPSCs, IPSCF and IPSCS) in neocortical Cajal-Retzius cells are observed. In this study, zolpidem, a benzodiazepine agonist that specifically modulates gamma-aminobutyric acid type A receptors (GABAARs) containing gamma2 subunit, was used to characterize GABAARs mediating IPSCF and IPSCS.
Andre Kamkin   +4 more
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Postsynaptic blockade of inhibitory postsynaptic currents by plasmin in CA1 pyramidal cells of rat hippocampus

Brain Research, 1997
We have shown previously that plasmin facilitated the generation of long-term potentiation (LTP) in CA1 and dentate region of rat hippocampus. In the present study, we investigated the effects of plasmin on postsynaptic currents in CA1 pyramidal neurons of rat hippocampal slices.
Norio Matsuki   +3 more
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Single postsynaptic channel currents in tissue cultured muscle

Nature, 1979
Some of the most compelling evidence for the existence of ionic channels in cell membranes comes from direct recording of quantised current jumps generated by the opening and closing of individual channels. Single-channel jumps have been extensively studied for lipid bilayer membranes doped with various channel-forming additives.
Harold Lecar, Meyer B. Jackson
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Postsynaptic currents at the Mauthner fiber giant synapse of the hatchetfish

Brain Research, 1985
Postsynaptic currents (PSCs) at the giant synapse between Mauthner and giant fibers of the hatchetfish Gasteropelecus were studied under voltage clamp. This axo-axonic synapse lies in the central nervous system beneath the floor of the 4th ventricle where electrodes can be closely positioned both pre- and postsynaptically.
W.D. Huse   +2 more
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Postsynaptic currents in different types of frog muscle fibre

Pfl�gers Archiv European Journal of Physiology, 1982
Miniature end-plate currents (mepcs) were recorded from fast and slow muscle fibres in two muscles, m. cruralis and m. ileofibularis, under voltage clamp or extracellularly. Both fibre types showed an identical sensitivity to α-bungarotoxin, and an exponential dependence of mepc decay time-constant upon membrane potential, but there were some important
V. A. Snetkov   +3 more
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A rise in postsynaptic Ca 2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons

Neuron, 1994
We have investigated the site of expression of the potentiation of excitatory postsynaptic currents (EPSCs) induced by the activation of postsynaptic voltage-sensitive Ca2+ channels, by examining the effect of depolarizing pulses on miniature (m) EPSCs and responses to AMPA.
Toshiya Manabe   +2 more
openaire   +3 more sources

Relation between rise times and amplitudes of GABAergic postsynaptic currents

Journal of Neurophysiology, 1996
1. We recorded rise times and amplitudes of spontaneous GABAergic inhibitory postsynaptic currents (IPSCs) in melanotropes of Xenopus laevis. Average rise times did not vary with amplitude, but the rise times of larger IPSCs were less variable. A simple linear one-step Markov model for channel opening following the binding of a transmitter molecule ...
Bier, M., Kits, K., Borst, J.
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Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS

Current Opinion in Neurobiology, 1994
Excitatory postsynaptic currents in neurones of the central nervous system have a dual-component time course that results from the co-activation of AMPA/kainate-type and NMDA-type glutamate receptors. New approaches in electrophysiology and molecular biology have provided a better understanding of the factors that determine the kinetics of excitatory ...
Jonas, P., Spruston, N.
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Voltage sensitivity of inhibitory postsynaptic currents inAplysia buccal ganglia

Brain Research, 1976
Inhibitory postsynaptic currents (IPSCs) which were recorded in voltage-clamped neurones in buccal ganglia of Aplysia were blocked by D-tubocurarine and lengthened by prostigmine. Their amplitude varied with membrane potential and the mean null potential was --58 mV. The conductance change producing the IPSCs was in the range 1-5 x 10 -7 ~2-1.
Adams, David J   +2 more
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Developmental change of GABAergic postsynaptic current in rat periaqueductal gray

Neuroscience Letters, 2005
The present study was designed to examine developmental changes of GABAergic spontaneous miniature inhibitory postsynaptic currents (mIPSCs) in periaqueductal gray (PAG) neurons mechanically isolated from young (12- to 18-day) and adult (8- to 12-week) rats.
Byung-Il Min   +3 more
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