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Single-Channel Currents and Postsynaptic Drug Actions
1986In single-channel recordings, the gating transitions of individual ionic channels appear as a stochastic process. The description of the random transitions of a channel between its discrete conductance states complements the kinetic picture of the gating process derived from macroscopic experiments such as voltage clamp, noise analysis, or gating ...
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SICNN with Chaotic/Almost Periodic Postsynaptic Currents
2019This chapter is of big interest to those readers, who look for three subjects of investigation: neural networks theory; nonlinear oscillations; and development of results for discontinuous almost periodicity to continuous dynamics and chaos. Thus, we will demonstrate that the technique developed in our papers can be applied to the construction of ...
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Influence of the extracellular ionic environment on ganglionic fast excitatory postsynaptic currents
Brain Research, 1985The influence of changing the extracellular sodium or calcium concentration as well as the addition of strontium or magnesium on characteristics of nicotinic fast excitatory postsynaptic currents (EPSCs) has been studied in voltage-clamped sympathetic ganglion B cells of the bullfrog.
Darcy S. Neel+2 more
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Valproate reduced excitatory postsynaptic currents in hippocampal CA1 pyramidal neurons
Neuropharmacology, 2004Valproate (VPA) is one of the most widely used antiepileptic drugs, and it is also increasingly used for the treatment of neuropsychological disorders and neuropathic pain, as well as migraine prophylaxis. However, the underlying cellular mechanisms of VPA on the synaptic physiology remain unclear.
Eduardo D. Martín, Miguel A. Pozo
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Ghrelin Potentiates Miniature Excitatory Postsynaptic Currents in Supraoptic Magnocellular Neurones
Journal of Neuroendocrinology, 2009Ghrelin is an orexigenic peptide discovered in the stomach as a ligand of the orphan G‐protein coupled receptor, and participates in the regulation of growth hormone (GH) release. Previous studies have demonstrated that ghrelin suppressed water intake and stimulated the secretion of arginine vasopressin in rats. We examined the effect of ghrelin on the
Hitoshi Suzuki+8 more
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Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum
Neuroscience, 1998Electrophysiological consequences of activation of cannabinoid receptors have been mostly investigated on neuronal cell lines and on cells transfected with cannabinoid receptors. The aim of the present experiments was to study cannabinoid effects on identified neurons in situ.
Klaus Starke+4 more
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In Vitro Cellular & Developmental Biology - Animal, 2014
M. Hannan+4 more
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M. Hannan+4 more
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