Results 21 to 30 of about 9,516,972 (308)

Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]

open access: yes, 1979
Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin   +2 more
core   +1 more source

Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neurons in vitro [PDF]

open access: yes, 1987
1. The characteristics of long-duration inhibitory postsynaptic potentials (l-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from anin vitro slice preparation.
A. Constanti   +17 more
core   +1 more source

Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
core   +1 more source

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]

open access: yes, 2014
Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J   +2 more
core   +1 more source

Kappa Opioid Inhibition of Somatodendritic Dopamine Inhibitory Postsynaptic Currents [PDF]

open access: yesJournal of Neurophysiology, 2007
In the midbrain, dopamine neurons can release dopamine somatodendritically. This results in an inhibitory postsynaptic current (IPSC) within adjacent dopamine cells that occurs by the activation of inhibitory D2autoreceptors. Kappa, but not mu/delta, opioid receptors inhibit this IPSC.
Michael J. Beckstead   +2 more
openaire   +3 more sources

Convulsant actions of 4-aminopyridine on the guinea-pig olfactory cortex slice [PDF]

open access: yes, 1982
The effects of bath-applied 4-aminopyridine on neurones and extracellular potassium and calcium concentrations were recorded in slices of guinea-pig olfactory cortex. Neurones were orthodromically activated by stimulating the lateral olfactory tract.
Baranyi   +47 more
core   +1 more source

Dopaminergic Modulation of Excitatory Postsynaptic Currents in Rat Neostriatal Neurons [PDF]

open access: yesJournal of Neurophysiology, 1997
Umemiya, Masashi and Lynn A. Raymond. Dopaminergic modulation of excitatory postsynaptic currents in rat neostriatal neurons. J. Neurophysiol. 78: 1248–1255, 1997. γ-aminobutyric acid (GABA)-containing medium spiny neurons constitute ∼90% of the neuronal population in the neostriatum (caudate and putamen) and play an important role in motor ...
Masashi Umemiya, Lynn A. Raymond
openaire   +3 more sources

G protein-coupled receptors mediate a fast excitatory postsynaptic current in CA3 pyramidal neurons in hippocampal slices

open access: yesJournal of Neuroscience, 1995
Synaptic activation in the presence of competitive (D,L-APV,CNQX) and noncompetitive (MK-801,GYKI-52466) ionotropic glutamate receptor antagonists induced fast (10–90% rise time of 15–30 msec) postsynaptic responses in CA3 pyramidal neurons from acute ...
L. Miller, J. Petrozzino, J. Connor
semanticscholar   +1 more source

Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]

open access: yes, 1980
Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri   +36 more
core   +1 more source

Inhibition by riluzole of glycinergic postsynaptic currents in rat hypoglossal motoneurones [PDF]

open access: yesBritish Journal of Pharmacology, 1995
1. Riluzole has been shown to have beneficial effects in motoneurone disease, yet its effect on motoneurones is not known. To address this question, we investigated synaptic modulation by riluzole in hypoglossal motoneurones by recording glycinergic inhibitory postsynaptic currents evoked by stimulation of nearby single interneurones. 2.
Masashi Umemiya, Albert J. Berger
openaire   +3 more sources

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