Results 291 to 300 of about 156,710 (324)
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Postsynaptic Currents in Deep Cerebellar Nuclei

Journal of Neurophysiology, 2001
Postsynaptic currents were studied by whole cell recordings in visually identified large neurons of the deep cerebellar nuclei (DCN) in slices of 4- to 11-day-old mice. Spontaneous postsynaptic currents were abolished by the GABAAreceptor antagonist bicuculline and had a single-exponential decay with a mean time constant of 13.6 ± 3.2 (SD) ms ...
D. ANCHISI, B. SCELFO, TEMPIA, Filippo
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Postsynaptically different inhibitory postsynaptic currents in Cajal–Retzius cells in the developing neocortex

NeuroReport, 2008
Fast and slowly rising inhibitory postsynaptic currents (IPSCs, IPSCF and IPSCS) in neocortical Cajal-Retzius cells are observed. In this study, zolpidem, a benzodiazepine agonist that specifically modulates gamma-aminobutyric acid type A receptors (GABAARs) containing gamma2 subunit, was used to characterize GABAARs mediating IPSCF and IPSCS.
Anton, Dvorzhak   +4 more
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Inhibitory postsynaptic current in voltage-clamped crayfish muscle

Nature, 1976
THE current–voltage relationship provides important information about the mechanism of ionic permeation through membranes. In excitatory synapses the relationship between membrane potential and excitatory postsynaptic current (e.p.s.c.) has been extensively studied using the voltage-clamp method1–6. In the frog endplate it has been shown that the e.p.s.
K, Onodera, A, Takeuchi
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Single postsynaptic channel currents in tissue cultured muscle

Nature, 1979
Some of the most compelling evidence for the existence of ionic channels in cell membranes comes from direct recording of quantised current jumps generated by the opening and closing of individual channels. Single-channel jumps have been extensively studied for lipid bilayer membranes doped with various channel-forming additives.
M B, Jackson, H, Lecar
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Excitatory postsynaptic current model for synaptic thin-film transistors

Journal of Applied Physics, 2022
Synaptic devices that mimic biological neurons have attracted much attention for brain-inspired neuromorphic computing. Especially, synaptic thin-film transistors (TFTs) have emerged with simultaneous signal processing and information storage advantages.
Changik Im   +9 more
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Postsynaptic currents in different types of frog muscle fibre

Pfl�gers Archiv European Journal of Physiology, 1982
Miniature end-plate currents (mepcs) were recorded from fast and slow muscle fibres in two muscles, m. cruralis and m. ileofibularis, under voltage clamp or extracellularly. Both fibre types showed an identical sensitivity to α-bungarotoxin, and an exponential dependence of mepc decay time-constant upon membrane potential, but there were some important
V V, Fedorov   +3 more
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Postsynaptic blockade of inhibitory postsynaptic currents by plasmin in CA1 pyramidal cells of rat hippocampus

Brain Research, 1997
We have shown previously that plasmin facilitated the generation of long-term potentiation (LTP) in CA1 and dentate region of rat hippocampus. In the present study, we investigated the effects of plasmin on postsynaptic currents in CA1 pyramidal neurons of rat hippocampal slices.
A, Mizutani   +3 more
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Voltage sensitivity of inhibitory postsynaptic currents inAplysia buccal ganglia

Brain Research, 1976
Inhibitory postsynaptic currents (IPSCs) which were recorded in voltage-clamped neurones in buccal ganglia of Aplysia were blocked by D-tubocurarine and lengthened by prostigmine. Their amplitude varied with membrane potential and the mean null potential was --58 mV. The conductance change producing the IPSCs was in the range 1-5 x 10 -7 ~2-1.
Adams, David J   +2 more
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A rise in postsynaptic Ca 2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons

Neuron, 1994
We have investigated the site of expression of the potentiation of excitatory postsynaptic currents (EPSCs) induced by the activation of postsynaptic voltage-sensitive Ca2+ channels, by examining the effect of depolarizing pulses on miniature (m) EPSCs and responses to AMPA.
D J, Wyllie, T, Manabe, R A, Nicoll
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Relation between rise times and amplitudes of GABAergic postsynaptic currents

Journal of Neurophysiology, 1996
1. We recorded rise times and amplitudes of spontaneous GABAergic inhibitory postsynaptic currents (IPSCs) in melanotropes of Xenopus laevis. Average rise times did not vary with amplitude, but the rise times of larger IPSCs were less variable. A simple linear one-step Markov model for channel opening following the binding of a transmitter molecule ...
Bier, M., Kits, K., Borst, J.
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