Results 301 to 310 of about 156,710 (324)
Some of the next articles are maybe not open access.
Valproate reduced excitatory postsynaptic currents in hippocampal CA1 pyramidal neurons
Neuropharmacology, 2004Valproate (VPA) is one of the most widely used antiepileptic drugs, and it is also increasingly used for the treatment of neuropsychological disorders and neuropathic pain, as well as migraine prophylaxis. However, the underlying cellular mechanisms of VPA on the synaptic physiology remain unclear.
Eduardo D, Martín, Miguel A, Pozo
openaire +2 more sources
Neuroscience Letters, 1983
In opener muscle fibres of the crayfish claw excitatory postsynaptic currents activated by glutamate (1 . 10(-4)-5 . 10(-4) mol/l) were investigated by means of the noise analysis technique. For the apparent mean open time of glutamate-activated channels, tau noise = 1.15 ms +/- 0.16 (S.D., n = 24) resulted at membrane potentials between E = -60 mV and
openaire +2 more sources
In opener muscle fibres of the crayfish claw excitatory postsynaptic currents activated by glutamate (1 . 10(-4)-5 . 10(-4) mol/l) were investigated by means of the noise analysis technique. For the apparent mean open time of glutamate-activated channels, tau noise = 1.15 ms +/- 0.16 (S.D., n = 24) resulted at membrane potentials between E = -60 mV and
openaire +2 more sources
Ghrelin Potentiates Miniature Excitatory Postsynaptic Currents in Supraoptic Magnocellular Neurones
Journal of Neuroendocrinology, 2009Ghrelin is an orexigenic peptide discovered in the stomach as a ligand of the orphan G‐protein coupled receptor, and participates in the regulation of growth hormone (GH) release. Previous studies have demonstrated that ghrelin suppressed water intake and stimulated the secretion of arginine vasopressin in rats. We examined the effect of ghrelin on the
T, Yokoyama +8 more
openaire +2 more sources
Developmental change of GABAergic postsynaptic current in rat periaqueductal gray
Neuroscience Letters, 2005The present study was designed to examine developmental changes of GABAergic spontaneous miniature inhibitory postsynaptic currents (mIPSCs) in periaqueductal gray (PAG) neurons mechanically isolated from young (12- to 18-day) and adult (8- to 12-week) rats.
Eu-Teum, Hahm +3 more
openaire +2 more sources
Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS
Current Opinion in Neurobiology, 1994Excitatory postsynaptic currents in neurones of the central nervous system have a dual-component time course that results from the co-activation of AMPA/kainate-type and NMDA-type glutamate receptors. New approaches in electrophysiology and molecular biology have provided a better understanding of the factors that determine the kinetics of excitatory ...
Jonas, P., Spruston, N.
openaire +3 more sources
Postsynaptic Current Mediated by Metabotropic Glutamate Receptors in Cerebellar Purkinje Cells
Journal of Neurophysiology, 1998Tempia, Filippo, Maria Concetta Miniaci, Davide Anchisi, and Piergiorgio Strata. Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells. J. Neurophysiol. 80: 520–528, 1998. In rat cerebellar slices, repetitive parallel fiber stimulation evokes an inward, postsynaptic current in Purkinje cells with a fast ...
TEMPIA, Filippo +3 more
openaire +4 more sources
Modelling action of ionic channel blockers on postsynaptic currents
Neurophysiology, 1990A mathematical model of the effects of open (ionic) channel blockers on generation of postsynaptic current at the neuromuscular junction is described. Quantitative aspects of simple blocking action are analyzed as well as criteria by which blockade of ionic channels may be discriminated from modification of their activation kinetics.
V. A. Snetkov +3 more
openaire +1 more source
Fast excitatory postsynaptic currents in neurons of the rabbit pelvic plexus
Autonomic Neuroscience, 2002Fast excitatory postsynaptic currents have been recorded at 23-27 degrees C from rabbit pelvic plexus neurons by a two-electrode voltage-clamp technique. The synaptic current decay was bi-exponential with the fast and slow components characterized at -50 mV by mean time constants of 4.0 +/- 0.3 and 21.9 +/- 2.8 ms (n = 11), respectively.
Andrei Yu, Bobryshev, Vladimir I, Skok
openaire +2 more sources
Postsynaptic Currents Prior to Onset of Epileptiform Activity in Rat Microgyria
Journal of Neurophysiology, 2007Structural malformations of the cortex, arising as a result of genetic mutation or injury during development are associated with dyslexia, epilepsy, and other neurological deficits. We have used a rat model of a microgyral malformation to examine mechanisms of epileptogenesis.
A, Zsombok, K M, Jacobs
openaire +2 more sources
SICNN with Chaotic/Almost Periodic Postsynaptic Currents
2019This chapter is of big interest to those readers, who look for three subjects of investigation: neural networks theory; nonlinear oscillations; and development of results for discontinuous almost periodicity to continuous dynamics and chaos. Thus, we will demonstrate that the technique developed in our papers can be applied to the construction of ...
openaire +1 more source