Results 41 to 50 of about 156,710 (324)
PTPσ Controls Presynaptic Organization of Neurotransmitter Release Machinery at Excitatory Synapses
iScience, 2020 Summary: Leukocyte common antigen-related receptor tyrosine phosphatases (LAR-RPTPs) are evolutionarily conserved presynaptic organizers. The synaptic role of vertebrate LAR-RPTPs in vivo, however, remains unclear.
Kyung Ah Han +10 more
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Stimulus-specific adaptation at the synapse level in vitro. [PDF]
PLoS ONE, 2014 Stimulus-specific adaptation (SSA) is observed in many brain regions in humans and animals. SSA of cortical neurons has been proposed to accumulate through relays in ascending pathways.
Haitao Wang +3 more
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Dopaminergic Modulation of Excitatory Postsynaptic Currents in Rat Neostriatal Neurons [PDF]
Journal of Neurophysiology, 1997 Umemiya, Masashi and Lynn A. Raymond. Dopaminergic modulation of excitatory postsynaptic currents in rat neostriatal neurons. J. Neurophysiol. 78: 1248–1255, 1997. γ-aminobutyric acid (GABA)-containing medium spiny neurons constitute ∼90% of the neuronal population in the neostriatum (caudate and putamen) and play an important role in motor ...
M, Umemiya, L A, Raymond
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Frontiers in Neural Circuits, 2020 Corticofugal modulation of auditory responses in subcortical nuclei has been extensively studied whereas corticofugal synaptic transmission must still be characterized.
Jiyao Qi +5 more
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Mechanisms of synaptic depression at the hair cell ribbon synapse that support auditory nerve function [PDF]
, 2017 Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane potentials, the so called “receptor potentials.” Ribbon synapses between IHCs and auditory nerve neurons are responsible ...
Goutman, Juan Diego
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Frontiers in Systems NeuroscienceStudies of the microtubule-associated protein, tau suggest its promise as a potential target for epilepsy disease modification, but mechanisms underlying tau’s effects on seizures are not well-defined.
Madeleine C. Moseley +10 more
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Postsynaptic protein kinase a reduces neuronal excitability in response to increased synaptic excitation in the Drosophila CNS [PDF]
, 2003 Previous work has identified a role for synaptic activity in the development of excitable properties of motoneurons in the Drosophila embryo. In this study the underlying mechanism that enables two such neurons, termed aCC and RP2, to respond to ...
Baines, Richard A.
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Neuropsychopharmacology Reports, 2023 Binge‐like exposure to ethanol during the brain growth spurt triggers apoptotic neurodegeneration in multiple brain regions, including the retrosplenial cortex, a brain region that is part of the hippocampal‐diencephalic‐cingulate memory network. This is
Clark W. Bird, Carlos F. Valenzuela
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LRP4 is required for the olfactory association task in the piriform cortex
Cell & Bioscience, 2022 Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan +12 more
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Miniature Inhibitory Postsynaptic Currents in CA1 Pyramidal Neurons After Kindling Epileptogenesis [PDF]
Journal of Neurophysiology, 1999 Miniature inhibitory postsynaptic currents (mIPSCs) were measured in CA1 pyramidal neurons from long-term kindled rats (>6 weeks after they reached the stage of generalized seizures) and compared with controls. A large reduction in the number of mIPSCs was observed in a special group of large mIPSCs (amplitude >75 pA). The frequency of mIPSCs in
Wierenga, C.J., Wadman, W.J.
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