Results 61 to 70 of about 9,516,972 (308)

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats.

Iranian journal of medical sciences, 2016
Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown. We aimed to elucidate the effects of different concentrations of ketamine on the glutamatergic synaptic transmission of the neurons in the
Chengdong Yuan, Yajun Zhang, Yu Zhang, Song Cao, Yuan Wang, Bao Fu, Tian Yu   +6 more
openaire   +2 more sources

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source

Nitric oxide and synaptic function [PDF]

, 1994
The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
core   +1 more source

Current status of PET imaging in Huntington’s disease

European Journal of Nuclear Medicine and Molecular Imaging, 2016
PurposeTo review the developments of recent decades and the current status of PET molecular imaging in Huntington’s disease (HD).MethodsA systematic review of PET studies in HD was performed.
G. Pagano, F. Niccolini, M. Politis
semanticscholar   +1 more source

Highly Efficient n‐Type Doped Single‐Crystalline Perylene Diimide Microwires via Solution Processing for High‐Performance Photosensors and Photo‐Neuromorphic Devices

Advanced Materials Technologies, EarlyView.
Solution‐processed high‐performance n‐type doped single‐crystalline organic semiconductor microwires (MWs) are reported. n‐Type dopants are located at the terrace edge of the MW, resulting in rapid doping and high interaction. n‐doped MWs show 5,000 times enhanced photosensitivity than evaporated films and high photo‐neuromorphic characteristics by ...
Yonghee Kim, Hye Won Lee, Min Ju Jung, Sangwook Lee, Joon Hak Oh, Eun Kwang Lee   +5 more
wiley   +1 more source

Toward Advancement of Fabrication Techniques of Neuromorphic Computing Devices Based on 2D Materials

Advanced Materials Technologies, EarlyView.
This review highlights emerging fabrication techniques of 2D material‐based neuromorphic devices, emphasizing proximity vapor transfer for bioinspired optoelectronic applications. Abstract The growing necessity for power‐efficient and cognitive computation mechanisms has driven progress in neuromorphic computing which seeks to imitate the synaptic ...
Shubham Umeshkumar Gupta, Malkeshkumar Patel, Naveen Kumar, László Pohl, Min‐Joon Park, Sung‐Min Youn, Chaewhan Jeong, Joondong Kim   +7 more
wiley   +1 more source

The Glutamatergic Aspects of Schizophrenia Molecular Pathophysiology: Role of the Postsynaptic Density, and Implications for Treatment

Current Neuropharmacology, 2014
Schizophrenia is one of the most debilitating psychiatric diseases with a lifetime prevalence of approximately 1%. Although the specific molecular underpinnings of schizophrenia are still unknown, evidence has long linked its pathophysiology to ...
F. Iasevoli, C. Tomasetti, E. Buonaguro, A. de Bartolomeis   +3 more
semanticscholar   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Depolarization-activated potentiation of the T fiber synapse in the blue crab [PDF]

, 1993
The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission.
Lin, J.-W., Llinas, R.
core  

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

Advanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu, Jin‐Yin Huang, Xing‐Zhe Xu, Ji‐Yu Sun, Dan‐Ni Zou, Jia‐Yao Zhang, Chen Chi, Qi Zhang, Wei‐Cai Liu   +8 more
wiley   +1 more source