Results 201 to 210 of about 8,644,509 (305)

Persisting Region-Specific Microglia Activation and Synaptic Imbalance During Remission in a DSS-Induced Colitis Model. [PDF]

Glia
Morton L, Villafuerte LE, Garza AP, Lindemann N, Wider-Eberspächer E, Bruder D, Dunay IR.   +6 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Subcortical Dendritic Scaffolding in Autism Spectrum Disorder: A Testable ANK2-SCN2A-SHANK Framework. [PDF]

Int J Mol Sci
Cacciato-Salcedo S, Lao-Rodriguez AB, Petrinovic MM, Malmierca MS.   +3 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Self-Powered Neuromorphic Systems Based on Tribotronics Synaptic Devices. [PDF]

Small
Shrestha K, Akbari MK, Anbari AP, Pandey P, Zhuiykov S.   +4 more
europepmc   +1 more source

Expanding the electroclinical spectrum of TANC2‐related disorders: Lennox–Gastaut syndrome and related developmental epileptic phenotypes

Epilepsia Open, EarlyView.
Abstract Objective Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...
Lorenzo Perilli, Carlotta Stipa, Gianmichele Villano, Laura Licchetta, Leo Strothmann, Robin Tobias Jauss, Gerhard Josef Kluger, Raffaella Minardi, NETRE consortium, Giuseppe Gobbi, Salvatore Grosso, Francesca Bisulli, Pasquale Striano   +12 more
wiley   +1 more source

Umbelliferone-induced recovery of postsynaptic density structure revealed by the reanalysis of public electron microscopy data. [PDF]

Appl Microsc
Choi GY, Choi H, Lee S, Kweon HS.
europepmc   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

p75 neurotrophin receptor preserves neuromuscular synapse stability and muscle strength during aging. [PDF]

NPJ Aging
Pérez V, Aedo-Cares S, Bermedo-García F, Mella J, Uribe-Martínez C, Bronfman FC, Henríquez JP.   +6 more
europepmc   +1 more source

Organic photonic synaptic transistors for bionic vision: From spectral engineering to flexible intelligent perception

FlexMat, EarlyView.
Different wavelength photonic synapses are used for biomimetic visual applications. Abstract Bionic intelligent visual perception systems have significant application prospects in fields such as autonomous driving and robotics, medical imaging and auxiliary diagnosis, security and monitoring.
Longlong Jiang, Shan Wu, Silu Feng, Heyi Huang, Wangyu Wu, Hong Han, Yao Ni   +6 more
wiley   +1 more source