Results 231 to 240 of about 119,060 (284)

Membrane proeteins as markers for normal and neoplastic endocrine cells [PDF]

open access: yes, 1993
Gratzl, Manfred   +2 more
core  

ZNF282 Promotes Colorectal Cancer Progression Possibly via E2F1 Activation

open access: yesCancer Science, EarlyView.
ZNF282 is a zinc finger protein overexpressed in colorectal cancer that facilitates tumor progression by promoting cell cycle progression via E2F1 activation. Our study demonstrates that ZNF282 expression is associated with poor prognosis and may serve as a novel prognostic biomarker and therapeutic target. ABSTRACT Colorectal cancer (CRC) is a leading
Tadashi Abe   +23 more
wiley   +1 more source

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance

open access: yesCancer Science, EarlyView.
In this study, we focused on SUMOylation, a posttranslational modification, and investigated the importance of its consensus sequence in MAFK. We demonstrated that the non‐SUMOylation mimic mutant MAFK (EA) impairs MAFK‐induced EMT, cellular migration and invasion, tumor and sphere formation, acquisition of stem‐like properties, and drug resistance ...
Thuy Linh Dang Cao   +7 more
wiley   +1 more source

Posttranslational transport of proteins in the assembly of mitochondrial membranes [PDF]

open access: yes, 1980
Harmey, Matthew A.   +6 more
core  

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

open access: yesCell Proliferation, EarlyView.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie   +10 more
wiley   +1 more source

Advances in the study of posttranslational modifications of histones in head and neck squamous cell carcinoma

open access: gold
Yang Xiao   +7 more
openalex   +1 more source

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