Results 211 to 220 of about 941,378 (248)
Glia, Volume 74, Issue 11, November 2026.Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton +6 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 11, Page 3868-3881, November 2026.ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima +4 more
wiley +1 more source
Identification of a Glycosylation‐Related Gene Prognostic Signature for Non–Small Cell Lung Cancer
The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.A ten‐glycosylation‐related‐gene (GRG) prognostic signature for non‐small cell lung cancer (NSCLC) was constructed using TCGA data. Differentially expressed GRGs were screened and refined by Cox and LASSO regression. The ten‐gene signature (including ADAMTS15, PCSK9, MUC2, and B3GNT3) stratified patients into high‐ and low‐risk groups with distinct ...
Qingtao Zhao +2 more
wiley +1 more source
First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique
Mass Spectrometry Reviews, Volume 45, Issue 6, Page 1064-1086, November/December 2026.ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley +1 more source
MedComm, Volume 7, Issue 11, November 2026.Cerebral cavernous malformation (CCM) gene complex deficiency dual‐regulates YAP activity via a “dual‐pronged” mechanism: relieving LATS‐mediated inhibition to license YAP nuclear translocation, and promoting MAP3K3‐mediated YAP phosphorylation to stabilize YAP–KLF4 association.
Tingting Ye +11 more
wiley +1 more source
Posttranslational modification of plant microtubules. [PDF]
Plant Signal Behav, 2019 Gardiner J.
europepmc +1 more source
Atherosclerosis: From Pathogenesis to Therapeutic Interventions
MedComm, Volume 7, Issue 11, November 2026.The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou +9 more
wiley +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Protein Science, Volume 35, Issue 11, November 2026.Abstract Non‐standard amino acids (ncAAs) together with synthetic additions (like caps and linkers) are of wide interest for protein design and pharmaceutical optimization, as they can improve physicochemical properties and possibly reshape protein structure. Their inclusion in experimental structures has not been explored systematically.
Alex Waldherr +2 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.Eimeria tenella is one of the main causes of coccidiosis in poultry, with increasing drug resistance highlighting the need for alternate control strategies. This study identified Eimeria tenella AMA1 (EtAMA1) as a promising vaccine candidate through structural analysis, epitope prediction, immune simulation, and molecular docking, which demonstrated ...
Nooran Mahomed Rafeer +2 more
wiley +1 more source