Results 241 to 250 of about 119,060 (284)
Ovarian Aging: A Multifaceted Perspective on Mechanisms
A mechanistic network of ovarian aging, highlighting mitochondrial dysfunction as a central hub interconnected with genetic, metabolic, and inflammatory pathways.
Xiaoqing Zhang +9 more
wiley +1 more source
Transcriptional and Posttranslational Modifications of Titin [PDF]
Attila Borbély +2 more
openalex +1 more source
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina +11 more
wiley +1 more source
Resolution of distinct steps in mitochondrial protein import [PDF]
Bradshaw, Ralph A. +5 more
core
Competition between binding partners of yeast Pex3 affects peroxisome biology
Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange +5 more
wiley +1 more source
Development of a Conjugate Vaccine Targeting Human IgE for Long‐Term Prevention of Anaphylaxis
Allergy, EarlyView.
Vincent Serra, Laurent L. Reber
wiley +1 more source
We revealed the crystal structure of eKatE from atypical E. coli. eKatE exhibits a hydrogen‐peroxide‐sensitive major channel, a stabilized dimeric interface, an unusual covalent bond between C392 and Y415, and other distinctive features. These structural features contribute to its enhanced catalase activity compared to KatE in typical E.
Eunhee Koh +7 more
wiley +1 more source
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui +4 more
wiley +1 more source

