Results 61 to 70 of about 119,060 (284)

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Transcriptome Profiling and Bioinformatic Analysis of the Fourth-Stage Larvae of Angiostrongylus cantonensis

Iranian Journal of Parasitology, 2022
Background: To explore the transcriptome profiling of the fourth-stage larvae of Angiostrongylus cantonensis. Methods: Two groups of fourth-stage larvae were collected to extract total RNA in Zhejiang, China 2020. Then, mRNA was separated and reverse
Yue Guo, Hui Zhang, Haiyan Dong, Ming Ke Lu, Xiaoyu Li   +4 more
doaj   +1 more source

Enrichment and aggregation of topological motifs are independent organizational principles of integrated interaction networks

, 2011
Topological network motifs represent functional relationships within and between regulatory and protein-protein interaction networks. Enriched motifs often aggregate into self-contained units forming functional modules.
Anagha Joshi, Björklund, Brin, Bruno Nachtergaele, Csikász-Nagy, De Lathauwer, de Lichtenberg, Dobrin, Fiedler, Harbison, Hartwell, Huang, Kalir, Kashtan, Kashtan, Kellog, Kleinberg, Kraemer, Lee, Lee, Loch, Mazurie, McClellan, Mendenhall, Milo, Neely, Newman, Planta, Ptacek, Ravasz, Reguly, Shen-Orr, Solé, Solé, Spellman, Stark, Tan, Tom Michoel, Vázquez, Yeger-Lotem, Yeger-Lotem, Yosef, Yu, Yves Van de Peer, Zhang, Zhao   +45 more
core   +2 more sources

Biological and Biologically Inspired Functional Nanostructures: Insights into Structural, Optical, Thermal, and Sensing Applications

Advanced Materials, EarlyView.
Biological and biologically‐inspired functional nanostructures with structural, thermal, optical, and sensing applications are reviewed. The role of nanoscale features in biological materials on performance is described, and their blueprints are used for bio‐inspired nanomaterials, synthesized using advanced techniques (i.e., photolithography, bio ...
Chao Hsuan (Joseph) Sung, Taige Hao, Herry Fang, Andrew Tran Nguyen, Valentina Perricone, Haitao Yu, Wei Huang, Ezra Sarmiento, Adrian Francisco Duran Ornelas, Derek Lublin, Ric Wehling, Sanaz Farajollahi, Atsushi Arakaki, Dhriti Nepal, Nathan Patrick Lord, David Kisailus   +15 more
wiley   +1 more source

Protein post-translational modification regulates HIV-1 latency

生物医学转化
AIDS is a disease named acquired immunodeficiency syndrome, which caused by the human immunodeficiency virus (HIV). HIV can be divided into HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is a global pandemic that has caused serious harm.
Wu Tong, Wang Tiantian, Deng Kai
doaj   +1 more source

Purification and properties of glyceraldehyde-3-phosphate dehydrogenase from the skeletal muscle of the hibernating ground squirrel, Ictidomys tridecemlineatus [PDF]

PeerJ, 2014
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the skeletal muscle of euthermic and torpid Ictidomys tridecemlineatus was purified to electrophoretic homogeneity using a novel method involving Blue-agarose and Phenyl-agarose chromatography ...
Ryan A.V. Bell, Jeffrey C. Smith, Kenneth B. Storey   +2 more
doaj   +2 more sources

SUMOylation of nuclear actin [PDF]

, 2009
Actin, a major component of the cytoplasm, is also abundant in the nucleus. Nuclear actin is involved in a variety of nuclear processes including transcription, chromatin remodeling, and intranuclear transport.
Alessandro Arduini, Aslan, Ball, Camacho, Camacho, Carlos J. Camacho, Chik, Chuang, Comeau, Comeau, Dantan-Gonzalez, Dignam, dos Remedios, Dundr, Field, Frances V. Fuller-Pace, Hay, Hofmann, Hofmann, Jacobs, James L. Lessard, Jockusch, Johnson, Kalderon, Karakozova, Kozakov, Kudo, Kudryashova, Lin, Lorenz, Louvet, Mandell, Matic, Matsuzaki, McDonald, Panse, Pendleton, Pestic-Dragovich, Posern, Primal de Lanerolle, Reverter, Rodriguez, Rosas-Acosta, Samantha M. Nicol, Schoenenberger, Schoenenberger, Stuven, Thom, Vertegaal, Wada, Wang, Westphal, Wilma A. Hofmann   +52 more
core   +5 more sources

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. [PDF]

, 2019
Amyloid-β (Aβ) harbors numerous posttranslational modifications (PTMs) that may affect Alzheimer's disease (AD) pathogenesis. Here we present the 1.1 Å resolution MicroED structure of an Aβ 20-34 fibril with and without the disease-associated PTM, L ...
Boyer, David R, Cascio, Duilio, Clarke, Steven G, Eisenberg, David S, Gonen, Tamir, Richards, Logan S, Sawaya, Michael R, Warmack, Rebeccah A, Zee, Chih-Te   +8 more
core  

Lumpability Abstractions of Rule-based Systems [PDF]

, 2010
The induction of a signaling pathway is characterized by transient complex formation and mutual posttranslational modification of proteins. To faithfully capture this combinatorial process in a mathematical model is an important challenge in systems ...
Ana Sokolova, Christel Baier, Christel Baier, Christopher T. Walsh, D. Kannan Jianjun Paul Tian, Donald A. McQuarrie, Donald Gross, Elaine Murphy, Gabriel Ciobanu, Gerardo Rubino, Gerardo Rubino, Heinz Koeppl, Holger Conzelmann, Holger Hermanns, J'er^ome Feret, J. G. Kemeny, Jane Hillston, Jeremy Sproston, Jerome Feret, Jerome Feret, John Kemeny, Jos'ee Desharnais, Kim G. Larsen, Laurent Doyen, Maciej Koutny, Michael L. Blinov, Peter Buchholz, Peter Buchholz, Roger B. Sidje, Tatjana Petrov, Thomas A. Henzinger, Thomas G. Kurtz, Thomas Henzinger, Vincent Danos, Vincent Danos, William S. Hlavacek, William S. Hlavacek   +36 more
core   +7 more sources