Results 191 to 200 of about 1,714,984 (295)

Experimentally informed, quantitative photocycle model of the light-gated potassium channel WiChR. [PDF]

Biophys J
Ohnemus S, Tillert L, De Zio R, Tifrea RA, Leemisa AN, Beyer S, Kohl P, Timmermann V, Schneider-Warme F, Vierock J.   +9 more
europepmc   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

RNA targeting therapy for a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death. [PDF]

Nat Commun
Golinski SR, Soriano K, Briegel AC, Burke MC, Tang S, Carvill GL, Sherrill E, Lentucci C, Yu TW, Nakayama T, Hu R, Smith RS.   +11 more
europepmc   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Striatal neuron dysfunction in C9ORF72-FTD/ALS is driven by AIS and potassium channel dysregulation.

Cell Rep
Pasniceanu IS, Atwal MS, Santos Souza CD, Moll T, King M, Treanor C, Cabezas de la Fuente D, West RJH, Ferraiuolo L, Livesey MR.   +9 more
europepmc   +1 more source

Genetic Variants in Potassium Channel Genes and Their Clinical Implications in Kazakhstani Patients with Cardiac Arrhythmias. [PDF]

J Pers Med
Chamoieva A, Rakhimova S, Abilova Z, Akhmetova A, Akilzhanova G, Zhalbinova M, Daniyarov A, Akilzhanov K, Molkenov A, Kairov U, Kuanysheva A, Shaimardanov N, Abdrakhmanov A, Bekbossynova M, Akilzhanova A.   +14 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Bioactive lipid-mediated structural and functional regulation of the essential human potassium channel Kir7.1. [PDF]

Nat Commun
Niu Q, Vu S, Xu Y, Qian M, Rudenko A, Ye J, Zeng J, Huang W, Covey DF, Zhang R, Fu Z, Lishko PV.   +11 more
europepmc   +1 more source

Simultaneous Wastewater‐to‐Hydrogen Upgrading via Mechanically Driven Piezocatalysis Over Ag‐ZnO Nanorods

Advanced Science, EarlyView.
A piezocatalytic strategy enables simultaneous wastewater purification and hydrogen generation by harnessing mechanical energy. Complementary piezo‐induced charges are selectively directed toward oxidation and reduction pathways, achieving efficient pollutant degradation and continuous H2 evolution.
Yiqing Wei, Jianghai Huang, Yejunchi Zhang, Yang Wang, Dongmei Li, Chaogang Ban, Peng Yu, Jiangping Ma, Zhenxiang Cheng   +8 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source