Results 121 to 130 of about 3,077,235 (395)

Voltage-gated potassium channels as a potential therapeutic target for the treatment of neurological and psychiatric disorders

open access: yesFrontiers in Cellular Neuroscience
Voltage-gated potassium channels are a widely distributed subgroup of potassium channels responsible for the efflux of potassium in the repolarisation of the cell membrane, and hence contribute to the latency and propagation of action potentials. As they
Isabel E. Faulkner   +4 more
doaj   +1 more source

A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction [PDF]

open access: yes, 2018
A-type voltage-gated potassium (Kv) channels are major regulators of neuronal excitability that have been mainly characterized in the central nervous system. By contrast, there is a paucity of knowledge about the molecular physiology of these Kv channels
Covarrubias, Manuel   +3 more
core   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Tuning the Electronic Structure and Spin State of Fe─N─C Catalysts Using an Axial Oxygen Ligand and Fe Clusters for High‐Efficiency Rechargeable Zinc–Air Batteries

open access: yesAdvanced Functional Materials, EarlyView.
A FeN4─O/Clu@NC‐0.1Ac catalyst containing atomically‐dispersed FeN4─O sites (medium‐spin Fe2+) and Fe clusters delivered a half‐wave potential of 0.89 V for ORR and an overpotential of 330 mV at 10 mA cm−2 for OER in 0.1 m KOH. When the catalyst was used in a rechargeable Zn–air battery, a power density of 284.5 mW cm−2 was achieved with excellent ...
Yongfang Zhou   +8 more
wiley   +1 more source

Potassium Channels and Neurovascular Coupling

open access: yesCirculation Journal, 2010
Neuronal activity is communicated to the cerebral vasculature so that adequate perfusion of brain tissue is maintained at all levels of neuronal metabolism. An increase in neuronal activity is accompanied by vasodilation and an increase in local cerebral blood flow.
Dunn, Kathryn M., Nelson, Mark T.
openaire   +3 more sources

Single Solid‐State Ion Channels as Potentiometric Nanosensors

open access: yesAdvanced Functional Materials, EarlyView.
Single gold nanopores functionalized with mixed self‐assembled monolayers act as solid‐state ion channels for direct, selective potentiometric sensing of inorganic ions (Ag⁺). The design overcomes key miniaturization barriers of conventional ion‐selective electrodes by combining low resistivity with suppressed loss of active components, enabling robust
Gergely T. Solymosi   +4 more
wiley   +1 more source

Understanding mitochondrial potassium channels: 33 years after discovery

open access: yesActa Biochimica Polonica
Mitochondrial investigations have extended beyond their traditional functions, covering areas such as ATP synthesis and metabolism. Mitochondria are now implicated in new functional areas such as cytoprotection, cellular senescence, tumor function and ...
Adam Szewczyk
doaj   +1 more source

Role of various potassium channels in caffeine-induced aortic relaxation in rats

open access: yesSaudi Journal of Medicine and Medical Sciences, 2016
Background: Studies done on caffeine-induced changes in aortic rings have demonstrated inconclusive results. Moreover, the role of various potassium channels in caffeine-induced effects has not been explored so far.
Rabia Latif, Ahmed Badar
doaj   +1 more source

Monte Carlo study of gating and selection in potassium channels

open access: yes, 2011
The study of selection and gating in potassium channels is a very important issue in modern biology. Indeed such structures are known in all types of cells in all organisms where they play many important functional roles.
A. L. Hodgkin   +6 more
core   +1 more source

Molecular Cloning and Functional Expression of KCNQ5, a Potassium Channel Subunit That May Contribute to Neuronal M-current Diversity [PDF]

open access: hybrid, 2000
Christian Johann Lerche   +6 more
openalex   +1 more source

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