Results 61 to 70 of about 268,685 (303)

Ammonium toxicity and potassium limitation in yeast. [PDF]

open access: yesPLoS Biology, 2006
DNA microarray analysis of gene expression in steady-state chemostat cultures limited for potassium revealed a surprising connection between potassium and ammonium: potassium limits growth only when ammonium is the nitrogen source.
David C Hess   +3 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Synthesis and characterization of new potassium-containing argyrodite-type compounds

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2019
Potassium halogenthiophosphates K6PS5Br and K6PS5Cl as well as halogen-free K7PS6 compound were synthesized using the two-step technique from elemental substances as well as potassium halides.
I.P. Studenyak
doaj   +1 more source

NATURAL COMPOUNDS FOR CONTROLLING SUCKING PESTS INFESTING FABA BEAN IN ASSUIT GOVERNORATE [PDF]

open access: yesJournal of Plant Protection and Pathology, 2008
A field experiment was conducted in Assiut Governorate during the winter seasons of 2006/07 and 2007/08 to evaluate some natural compound (Vertemic 1.8, RM 131, Super-Misrona oil, Potassium solution and Micro-elements) in addition to fintera thion as a ...
M. Ahmed,
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Forms of potassium and sodium in some species of grasses and herbage

open access: yesActa Agrobotanica, 2013
The forms of occurence of potassium and sodium were studied in the grasses Dactylis glomerata L., Poa annua L., Festuca rubra L. and dendelion (Taraxacum officinale Web.) treated with increasing mineral fertilizer doses, magnesium and microelements ...
Grzegorz Nowak, Henryk Panak
doaj   +1 more source

THE HYDROLYSIS OF THE COMPOUND OF POTASSIUM WITH IRRADIATED GRAPHITE [PDF]

open access: yes, 1955
Potassium, the reaction product of graphite with potassium, and the reaction product of irradiated graphite with potassium were subjected to hydrolysis. The gases evolved from the respective samples were analyzed mass spectroscopically. Hydrocarbons (methane and a trace of ethane) were found in the gas evolved from the irradiated graphite compound only,
Primak, W.L., Quarterman, L.A.
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond.

open access: yes, 2021
Two-pore domain potassium (K2P) channels stabilize the resting membrane potential of both excitable and nonexcitable cells and, as such, are important regulators of cell activity.
Veale, E.L.   +4 more
core   +1 more source

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