SALT OVERLY SENSITIVE 1 Na<sup>+</sup>/H<sup>+</sup> Exchanger Operates in Mature Root Zone and Is a Major Contributor to Root Na<sup>+</sup> Exclusion During Shoot-to-Root Na<sup>+</sup> Recirculation. [PDF]
ABSTRACT The Na+/H+ antiporter SALT OVERLY SENSITIVE 1 (SOS1) is a key component of Na+ exclusion and plant salt tolerance. Although previous studies have suggested that SOS1 functions in both the root apex and mature root zone, their contributions remain unclear due to limited methodological resolution and originated mostly from transcriptional ...
Nagata T +9 more
europepmc +2 more sources
A Human Mass Balance and Metabolism Study of [<sup>14</sup>C]-Ubrogepant in Healthy Male Adults. [PDF]
Abstract Ubrogepant is a calcitonin gene–related peptide receptor antagonist approved for the acute treatment of migraine with or without aura in adults. The mass balance and metabolism of ubrogepant was evaluated in six healthy male adults administered a single oral dose of [14C]‐ubrogepant 50 mg (∼200 µCi).
Boinpally RR +13 more
europepmc +2 more sources
Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm +2 more
wiley +1 more source
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton +17 more
wiley +1 more source
Magnetic Evolution of Super‐Earth Exoplanets With a Basal Magma Ocean
Abstract Habitability of super‐Earths likely requires self‐sustained magnetic fields to shield their atmospheres from stellar forcing. Extreme pressures and temperatures probably produce a long‐lived basal magma ocean (BMO), a potential source for these fields.
Victor Lherm +2 more
wiley +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source
Natural Radioactivity in Food Stuff
The purpose of this research is to study the natural radioisotopes in different Iraqi food as well as various fission products emitted during nuclear accidents worldwide.
A.M. AL-Jumaily, K. Abdul Jabar
doaj
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal +4 more
wiley +1 more source
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad +11 more
wiley +1 more source
Potential of Soils Natural Sorbents for Environmental Decontamination From 137Cs
ABSTRACT This study addresses the existing research gap concerning the lack of integrated data on the role of in situ soil components in the long‐term fixation of 137Cs under natural, protected, and non‐agricultural conditions. The contamination of ecosystems by radioactive isotopes, particularly 137Cs, represents a considerable environmental hazard ...
Katarzyna Szarłowicz +3 more
wiley +1 more source

