Results 71 to 80 of about 391,425 (242)

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter, Gyorgy Ovari, Anurag Kulkarni, Thomas Williams‐Fegredo, Carol Knevelman, Kyriacos Mitrophanous, Lee Davies, Farzad Foroutan, Matthew Townsend, Stephen Goldrick, Daniel G. Bracewell   +10 more
wiley   +1 more source

Detection of Viruses and Elimination of Sweet Potato Feathery Mottle Virus in High-Yielding Varieties of Sweet Potato (Ipomoea batatas) from Ethiopia

Agriculture
Sweet potato (Ipomoea batatas L. Lam.) is a major source of food in many parts of Ethiopia. In recent years, viral diseases have become the main threat to sweet potato production in Ethiopia.
Dereje Haile Buko, Carl Spetz, Trine (A.K.) Hvoslef-Eide   +2 more
doaj   +1 more source

Characterisation of Hardenbergia mosaic virus and development of microarrays for detecting viruses in plants [PDF]

, 2008
A virus causing chlorosis and leaf distortion in the Western Australian endemic legume Hardenbergia comptoniana was detected by biological indexing to Chenopodium quinoa and Nicotiana benthamiana. Enzyme linked immuno-sorbent assay (ELISA) using general
Webster, Craig Graham
core  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Comprehensive virome analysis of potato crops in Bangladesh reveals diverse viral communities and the first report of potato virus V

Virology Journal
Potato crops in Bangladesh are significantly threatened by viral diseases, underscoring the need for comprehensive virome profiling to inform sustainable management strategies.
Mst. Fatema Khatun, Myeonghwan Kwak, Jiho Jeon, Md. Motaher Hossain, Eui-Joon Kil   +4 more
doaj   +1 more source

Molecular Mechanisms of Potato Plant–Virus–Vector Interactions

Plants
Viral infections and their vector dynamics pose a major threat to potatoes (Solanum tuberosum L.) worldwide, urgently needing an integrated understanding of the molecular and ecological interactions in this tripartite system.
Roza Kenzhebekova, Alexandr Pozharskiy, Kamila Adilbayeva, Dilyara Gritsenko   +3 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Insecticides against Aphid Vectors of Potato Viruses.

Netherlands Journal of Agricultural Science, 1953
Experiments were carried out on potato in Holland in 1951 to investigate the effects of Systox (diethyl 2-(ethylmercapto)ethyl thiophosphate [demeton]) and DDT on the Aphid vectors of leaf-roll and virus Y, their natural enemies and the yield of tubers, and the effect of demeton on the spread of the two viruses [cf.
Hille Ris Lambers, D., Reestman, A.J., Schepers, A.   +2 more
openaire   +2 more sources

Potato viruses in central Saudi Arabia

, 1998
Ouchterlony agar double diffusion test aod ELISA were used to detect viruses infecting potato in Gassim and Riyadh, the two major regions for potato production in central Saudi Arabia.
Al-Shahwan, I.M., Abdalla, O.A., Al-Saleh, M.A.   +2 more
core