Results 101 to 110 of about 514,099 (251)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Hydroxamate HDAC inhibitors potency in mediating dentine regeneration: a review
The quality of the reparative dentin structure is influenced by the signaling molecules contained in the pulp-capping material applied. A tunnel defect has been found in reparative dentin under treatment with conventional pulp-capping materials.
Ariyani, A P +3 more
core +1 more source
Frontiers in PharmacologyIntroduction Binding affinity and functional potency are two distinct but pharmacologically related properties in ligand-receptor interactions. The molecular features influencing these two endpoints may differ, reflecting distinct physicochemical and ...
Verena Schöning +9 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Pengembangan Potensi Santri di Pondok Pesantren Nurul Huda Tegalsambi Jepara
An-Nawa: Jurnal Studi IslamCurrently, Islamic boarding schools are used as one of the non-formal educational institutions to increase the potential of students to be able to compete in the era of globalization, such as the Nurul Huda Tegalsambi Jepara Islamic boarding school.
Fitri Sorelah Affni, Azzah Nor Laila
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Evaluating the ligands potency to affect the fast inactivation of voltage-gated sodium channel
This repository contains files presented in the manuscript "Evaluating the ligands potency to affect the fast inactivation of voltage-gated sodium channel":docking of all investigated ligands (to both open-state and inactivated-state models of ...
Niklas, Beata
core +1 more source
Frontiers in Public HealthBackgroundThe prevalence of cannabis as the most commonly used illicit substance in the United States and around the globe is well-documented. Studies have highlighted a noticeable uptrend in the potency of cannabis in the United states.
Mahmoud A. ElSohly +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2006 Neonicotinoid insecticides are potent selective agonists of insect nicotinic acetylcholine receptors (nAChRs). Since their introduction in 1991, resistance to neonicotinoids has been slow to develop, but it is now established in some insect field ...
Denholm, I. +11 more
core +1 more source