Chronic-moderate ethanol exposure of L(tk-) cells expressing ? 4? 3? GABAA receptors reduces potency of allopregnanolone potentiation of GABA-evoked inward currents: Possible role of PKC [PDF]
Aim: To investigate the effect of chronic-moderate ethanol (CME) treatment upon direct activation and allosteric modulation of GABAA receptors, and to assess the sensitivity of these parameters to PKC inhibition in control and ethanol-treated cells ...
Barrett, I.D., Kelley, Stephen P.
core
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
IntroductionMany breast cancer therapeutics target the PI3K/AKT/mTOR oncogenic pathway. Development of resistance to the therapeutics targeting this pathway is a frequent occurrence.
Adrian Thornton +11 more
doaj +1 more source
Existence a ten, kdo omdlívá ve V(v)ěci Makropulos, Tažení stínů (moderny) a v Duchu (středoevropské) země // Existence and He, Who Faints at The Makropulos Affair, The Campaign of Shadows (Modernism) and The Spirit of the (Central European) Land [PDF]
This study is concerned with the swooning as one of the characteristic motifs of modernism, arising from a period of reflexive attention. First it will examine this in the dramas of Arthur Schnitzler Zug der Schatten and Frank Wedekind’s Erdgeist, then
Kristýna Celhofferová
doaj
Benzothiadiazole induces the accumulation of phenolics in strawberry [PDF]
We have studied the potency of benzothiadiazole against powdery mildew disease in strawberry under greenhouse conditions, where the disease can be a problem.
Hukkanen, Anne +3 more
core
Distinct agonist regulation of muscarinic acetylcholine M2-M3 heteromers and their corresponding homomers [PDF]
Each subtype of the muscarinic receptor family of G protein-coupled receptors is activated by similar concentrations of the neurotransmitter acetylcholine or closely related synthetic analogs such as carbachol. However, pharmacological selectivity can be
Alvarez-Curto, Elisa +3 more
core +1 more source
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash +4 more
wiley +1 more source
Lamivudine versus Entecavir for Newly Diagnosed Hepatitis B Virus-Related Hepatocellular Carcinoma
Background/AimsAntiviral therapy is a key component in the management of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients. However, whether the potent drug entecavir is more effective than a less potent drug, such as lamivudine, in
Jung Hee Kim +9 more
doaj +1 more source
A new framework for a high energy limit of quantum gauge field theories is introduced. Its potency is illustrated on a new derivation of the reggeization of the gluon.Comment: Latex, 9 pages + 2 figures as PS-file, extended version, to appear in Phys ...
A. A. Bhatti +36 more
core +3 more sources

