Results 201 to 210 of about 583,846 (360)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Triazole-based STING inhibitors. [PDF]

Bioorg Med Chem
Singh A, Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Rossetti T, Green RM, Humphries F, Thompson PR.   +9 more
europepmc   +1 more source

Benign prostatic hyperplasia treated with Staphysagria in LM potency: An evidence-based case report

Karunakara Moorthi, K.R. Siva Tharshini
openalex   +2 more sources

Homeopathic potencies of Opium in alcohol dependence: exploratory open-label study

, 2021
U. Adler, Ana Elisa Madureira Padula, Amarilys de Toledo César, Maristela Schiabel Adler, José Carlos Fernandes Galduràz   +4 more
openalex   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Behavioural Effects and Naloxone Effectiveness With New Synthetic Opioids. [PDF]

Drug Alcohol Rev
Nielsen S, Silva JP, Jones JD, Krotulski A, Poovendran D, Muzangizi D, Forte G, White J, Comer SD.   +8 more
europepmc   +1 more source

Traditional marijuana, high‐potency cannabis and synthetic cannabinoids: increasing risk for psychosis

World Psychiatry, 2016
Robin M. Murray, H. Quigley, D. Quattrone, Amir Englund, M. di Forti   +4 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Hydantion indolinones as AANAT inhibitors. [PDF]

Bioorg Med Chem Lett
Wandrey N, Boley J, Gómez-Galicia D, Hill M, Bach M, Gawrych S, Hagemeister M, Cole PA, Moxley MA, Thomas AA.   +9 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source