Results 221 to 230 of about 1,009,444 (403)

Potency Unassigned [PDF]

, 2020
openaire   +1 more source

Exploring antimicrobial potency and in silico analysis of rosemary and hibiscus bioactive compounds to be used in germicidal product [PDF]

Vaishnavi Shedge, Seema Sambrani
openalex   +1 more source

Enhanced Anticancer Potency of Hydroxytyrosol and Curcumin by PLGA-PAA Nano-Encapsulation on PANC-1 Pancreatic Cancer Cell Line [PDF]

, 2020
Mahdieh Farhoudi, Behrouz Shadman, Reza Chavoshi, Nasrin Seyyedsani, Elnaz Aghaei, Elham Taheri, Pouya Goleij, Saba Hajazimian, Vahidreza Karamad, Alireza Isazadeh, Behzad Baradaran   +10 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Mesenchymal stromal cell-derived extracellular vesicles in regenerative medicine: Standardisation, bioengineering and clinical translation. [PDF]

Regen Ther
Shimizu Y, Inoue Y, Matsuura N, Ishii T, Sowa Y, Sunami H, Ntege EH.   +6 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Investigating the impact of oxygen concentration on the assembly of human papillomavirus virus like particles. [PDF]

Sci Rep
Liu Y, Chen D, Gao W, Shen E, Chen X, Du X, Wang D, Zhou S, Zhang H, Yu X, Liu Y.   +10 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Structure-Guided Design of Peptide Inhibitors Targeting Class I Viral Fusion Proteins. [PDF]

Pathogens
Gonepudi NK, Baffour Awuah H, Xu W, Katte RH, Lu M.   +4 more
europepmc   +1 more source

Potency of Local Gracilaria sp. Extract as an Antibacterial against Skin Disease Pathogen

, 2021
Natalie Sandra Susanto, Aniek Prasetyaningsih, Kukuh Madyaningrana   +2 more
openalex   +1 more source