Results 41 to 50 of about 997,205 (406)
Finding the potency in planarians
Communications Biology, 2022 Planarian flatworms are well-known for their regenerative ability, which is dependent on a large population of adult stem cells, called neoblasts, at least some of which are pluripotent. Here, two recent studies are compared that have begun to address this fundamental question of whether all or only some neoblasts are pluripotent.
openaire +3 more sources
Does In Vitro Potency Predict Clinically Efficacious Concentrations?
Clinical pharmacology and therapy, 2020 The in vitro affinity of a compound for its target is an important feature in drug discovery, but what remains is how predictive in vitro properties are of in vivo therapeutic drug exposure.
R. Jansson-Löfmark +2 more
semanticscholar +1 more source
LifeIntroduction: Herein, we explore whether coil embolization (CE) is effective in treating veno-occlusive dysfunction (VOD). We present five cases with seven CE episodes and a narrative literature review.
Ko-Shih Chang +5 more
doaj +1 more source
Emergent Penile Venous Stripping for Treating Adolescent Impotence
LifeIntroduction: Traditional anatomy-based penile venous surgery is deemed inadequate. Based on revolutionary insights into penile vasculature, penile venous stripping (PVS) shows promise in treating adolescent erectile dysfunction (AED). We aimed to report
Ko-Shih Chang +4 more
doaj +1 more source
Isolation and Characterization of the Novel Botulinum Neurotoxin A Subtype 6
mSphere, 2018 Botulinum neurotoxins (BoNTs), the most potent toxins known to humans and the causative agent of botulism, exert their effect by entering motor neurons and cleaving and inactivating SNARE proteins, which are essential for neurotransmitter release.
Molly S. Moritz +4 more
doaj +1 more source
Jurnal Pendidikan Matematika dan IPA, 2020 Mushroom are cosmopolitan organisms which can emerge in a variety of environment, and around the university building is no exception.The goal of this study was to collect information on macrofungi diversity around IPB Unversity Campus Building in order ...
Ivan Permana Putra
doaj +1 more source
Frontiers in Public HealthBackgroundThe prevalence of cannabis as the most commonly used illicit substance in the United States and around the globe is well-documented. Studies have highlighted a noticeable uptrend in the potency of cannabis in the United states.
Mahmoud A. ElSohly +4 more
doaj +1 more source
Inhibitors of PD-1 in Non-Small Cell Lung Cancer: A Meta-Analysis of Clinical and Molecular Features
Frontiers in Immunology, 2022 ObjectivePD-1 inhibitors have become an indispensable treatment in Non-Small Cell Lung Cancer (NSCLC), but the potential predictive value of clinical and molecular features need to be clarified. The objective of the study was to study the potency of PD-1
Gengwei Huo +3 more
doaj +1 more source
Distinct agonist regulation of muscarinic acetylcholine M2-M3 heteromers and their corresponding homomers [PDF]
, 2015 Each subtype of the muscarinic receptor family of G protein-coupled receptors is activated by similar concentrations of the neurotransmitter acetylcholine or closely related synthetic analogs such as carbachol. However, pharmacological selectivity can be
Alvarez-Curto, Elisa +3 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source