Results 101 to 110 of about 468,716 (263)

GIS-based Analysis of the Impact of Mass Rapid Transit on Accessibility and Spatial Equity in Jakarta

Rekayasa Sipil
Mass rapid transit (MRT), inaugurated in 2019 by the DKI Jakarta Provincial Government, was designed to address the city's transportation challenges by improving accessibility and reducing spatial disparities.
Sony Sulaksono Wibowo, Liora Parulian Bitya Joanna Silaen, Ade Sjafruddin, Widyarini Weningtyas   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Earthquake scenario-specific framework for spatial accessibility analysis (SAA) of emergency shelters: a case study in Xichang City, Sichuan Province, China

Frontiers in Earth Science
The spatial accessibility of emergency shelters, indicating the difficulty of evacuation and rescue, is crucial for disaster mitigation and emergency management.
Ziyue Wang, Ziyue Wang, Jia Cheng, Chong Xu, Chong Xu   +4 more
doaj   +1 more source

Hemodialysis vascular access: The perils and potentials

Indian Journal of Nephrology, 2017
Banerjee, D., Jenkins, R.
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Publishing in Open-Access Journals: Potential Pitfalls

Journal of the Advanced Practitioner in Oncology, 2013
As most of you know, at the Journal of the Advanced Practitioner in Oncology (JADPRO) we do not charge a fee to US readers who subscribe to the journal. We do not charge potential authors to have their work reviewed by our blind review process, nor do we charge for publication.
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Investigating the potential accessibility to HIV pre-exposure prophylaxis via community pharmacies and sexual health clinics: a scoping review of two integrated care systems in London. [PDF]

BMC Health Serv Res
Alaa A, Mujong D, Lakhani S, Alter M, El-Osta A.   +4 more
europepmc   +2 more sources