Results 111 to 120 of about 542,663 (313)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Location, Regional Accessibility and Price Effects: Evidence from Twin Cities Home Sales [PDF]

open access: yes
Regional location factors, with measures of regional accessibility foremost among them, exert a strong influence on urban property markets. While accessibility represents an important regional-scale factor, more local influences such as proximity to ...
Michael Iacono, David Levinson
core  

Calculation of potential accessibility distance.

open access: yes, 2019
Calculation of potential accessibility distance.
Mohand Medjkane (7299995)   +6 more
core   +1 more source

Brexit – and its potential impact for open access in the UK

open access: yesInsights the UKSG journal, 2017
This article looks at the possible implications of Brexit for approaches to open access (OA) in the UK. It begins by sketching current issues in Brexit debates at the end of 2016 as the context into which discussions about open access are then placed.
openaire   +6 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Traffic Accessibility and the Effect on Firms and Population in 99 Austrian Regions [PDF]

open access: yes
In this paper we describe the EAR (regional economic accessibility) model to investigate the impact of the improvement of railroad infrastructure on regional GDP, population and firms growth in 99 Austrian regions.
Polasek, Wolfgang   +1 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Transforming Media Accessibility in Europe

open access: yes
In a rapidly evolving digital landscape, accessibility in media has emerged as a crucial frontier for inclusion, equality, and knowledge democracy. The present edited volume "Transforming Media Accessibility in Europe: Digital Media, Education and City ...

core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Testing the Temporal Stability of Accessibility Value in Residential Hedonic Prices [PDF]

open access: yes
Purpose – This paper bridges the gap between, on the one hand, supply-driven (urban form and transportation networks) and demand-driven (action-based) accessibility to urban amenities and, on the other hand, house price dynamics as captured through panel
Francois Des Rosiers   +2 more
core  

Home - About - Disclaimer - Privacy