Results 131 to 140 of about 542,663 (313)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Strategic assessment of transport infrastructure Plans on European integration. Application for the Spanish Strategic Transport and Infrastructure Plan 2005-2020

open access: yes, 2008
Traditional transport infrastructure assessment methodologies rarely include the full range of strategic benefits for the transportation system. One of these benefits is the contribution to cross-border integration.
López Suárez, Elena   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Perceived Accessibility [Elektronisk resurs] : Living a satisfactory life with help of the transport system

open access: yes, 2018
This thesis fills a gap in contemporary transport research and planning as it introduces perceived accessibility as a theoretical and methodological concept for incorporating the individual dimension of accessibility in current practice.
Zakrisson, Ingrid,   +3 more
core  

A framework to include socio-demographic characteristics in potential job accessibility levels in low-car and car-free development areas in the Netherlands

open access: yesJournal of Transport and Land Use
Car-free development has become popular in recent years due to concerns regarding transport-related health issues in urban areas as well as a growing trend toward sustainability and environmentally friendly living.
Rutger Meester   +2 more
doaj   +1 more source

Hemodialysis vascular access: The perils and potentials

open access: yesIndian Journal of Nephrology, 2017
Banerjee, D., Jenkins, R.
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

MODELING SPATIAL ACCESSIBILITY WITHIN DISCRETE CHOICE FRAMEWORK

open access: yes
Spatial accessibility is concerned with the opportunity that an individual at a given location possesses to participate in a particular activity or set of activities.
Ulimwengu, John M., Guo, Xiaoqi
core  

Social justice and the gap between potential and realized accessibility [PDF]

open access: yes, 2014
Accessibility is increasingly regarded as an object of social distribution, but the applicability of this premise to public policy depends on the extent to which the indicators of accessibility used actually measure people’s wellbeing.
Anciaes, PR
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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