Results 131 to 140 of about 542,663 (313)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Traditional transport infrastructure assessment methodologies rarely include the full range of strategic benefits for the transportation system. One of these benefits is the contribution to cross-border integration.
López Suárez, Elena +3 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
This thesis fills a gap in contemporary transport research and planning as it introduces perceived accessibility as a theoretical and methodological concept for incorporating the individual dimension of accessibility in current practice.
Zakrisson, Ingrid, +3 more
core
Car-free development has become popular in recent years due to concerns regarding transport-related health issues in urban areas as well as a growing trend toward sustainability and environmentally friendly living.
Rutger Meester +2 more
doaj +1 more source
Hemodialysis vascular access: The perils and potentials
Banerjee, D., Jenkins, R.
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
MODELING SPATIAL ACCESSIBILITY WITHIN DISCRETE CHOICE FRAMEWORK
Spatial accessibility is concerned with the opportunity that an individual at a given location possesses to participate in a particular activity or set of activities.
Ulimwengu, John M., Guo, Xiaoqi
core
Social justice and the gap between potential and realized accessibility [PDF]
Accessibility is increasingly regarded as an object of social distribution, but the applicability of this premise to public policy depends on the extent to which the indicators of accessibility used actually measure people’s wellbeing.
Anciaes, PR
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

