Investigating the potential accessibility to HIV pre-exposure prophylaxis via community pharmacies and sexual health clinics: a scoping review of two integrated care systems in London. [PDF]
BMC Health Serv ResAlaa A +4 more
europepmc +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A family of accessibility measures derived from spatial interaction principles
Transportation planning has long prioritized the efficiency of movement, or mobility. However, the concept of accessibility represents a more comprehensive evolution, shifting focus from mere movement to the potential to reach (i.e., spatially interact ...
Christopher D. Higgins +3 more
core
Potential accessibility versus real accessibility of pdf format: Analysis of the Spanish online newspapers [PDF]
, 2008 The accessibility of the internet contents are not limited nor to web pages or Xhtml format. In this work, is explained that pdf format is every time more and more used in the web to publish news information and for this reason it must be object of ...
Codina, Lluís, Voces, Ramón
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Explaining the location decision of moving firms using their mobility profile and the accessibility of locations [PDF]
This paper describes the research approach and first empirical results of the estimation of discrete choice models that describe the location decision of moving firms.
Michiel de Bok
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Accessibility and the digital media
openL'accessibilità nei media digitali è diventata una preoccupazione critica, che influenza milioni di utenti in tutto il mondo. Questa ricerca esplora l'attuale panorama delle funzionalità di accessibilità nei media digitali, esaminando anche il ...
ABDIN, MOUNIR
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Humanities & Social Sciences CommunicationsAs crucial fixed links of the transportation systems, high bridges play an essential role in overcoming geographical barriers in mountainous areas. Despite their importance, comprehensive evaluations of the collective spatial-temporal effects of multiple
Jiayuan Cai, Zilin Deng, Linna Li
doaj +1 more source