Results 101 to 110 of about 542,663 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Exploring the Immersive Potential of Accessibility Options for Deaf and Hard-of-Hearing Players

open access: yesImages
This study examines the implementation and effectiveness of accessibility options in digital games, focusing on their role in shaping immersive experiences for deaf and hard-of-hearing players. Using a mixed-methods approach, this research combines game
Joanna Pigulak
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Measuring regional cohesion effects of large-scale transport infrastructure investments - an accessibility approach [PDF]

open access: yes
Accessibility gains arising from transport infrastructure improvements are one of the key elements boosting a complex process involving transport, land use and regional development effects.
Elena Lopez
core  

The power of evolution: accessing the synthetic potential of P450s

open access: yesChemistry & Biology, 1999
Cytochromes P450 can catalyse hydroxylation reactions that are of considerable potential synthetic value, but a number of practical difficulties have hitherto prevented their use for this purpose. Recent advances, including intelligently designed laboratory evolution experiments, promise to overcome these obstacles, and to add P450s to the enzymatic ...
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

KNOWLEDGE OF POTENTIAL/ACCESSIBILITY OF FINANCIAL CREDITS IN RURAL AREAS IN OLT COUNTY [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2014
The orientation of research activity of present situation regarding the current level of financial credit in rural areasof the Olt county required to carry out investigations on both the borrowers (farms) and the lenders (banks,financial institutions) in
Corina CRUCERU
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Linguistic Accessibility for Small Language Cinema

open access: yes, 2016
Audiovisual accessibility is considered as a basic right. In a world where audiovisual material is more and more present, several measures have been taken in order to facilitate the access to it by people living with sensory disabilities; some of them at
Deogracias Horrillo, Marijo   +1 more
core   +1 more source

Ornamental potential of sweet potato accessions

open access: yesBioscience Journal, 2018
Sweet potato [Ipomoea batatas (L.) Lam.] is a multipurpose plant due to the different uses for its roots, leaves, and branches. The objective of this study was to evaluate the ornamental potential of sweet potato accessions from the Germplasm Bank of Embrapa Hortaliças, Brasilia, DF, Brazil.
de Sousa, Rosa maria de Deus   +5 more
openaire   +5 more sources

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