Results 101 to 110 of about 4,256,657 (280)

Low-energy expansion formula for one-dimensional Fokker-Planck and Schr\"odinger equations with asymptotically periodic potentials

open access: yes, 2011
We consider one-dimensional Fokker-Planck and Schr\"odinger equations with a potential which approaches a periodic function at spatial infinity. We extend the low-energy expansion method, which was introduced in previous papers, to be applicable to such ...
Gesztesy F   +8 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A New Method of Drawing the Potential Energy Surface [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1955
Abstract A new method of drawing the potential energy surface has been devised and compared with Eyring’s semi-empirical method. The points different from the latter method are that an appropriate function for the anti-bonding state of a diatomic molecule is assumed and the overlap integral is not ignored.
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Multidimensional replica-exchange method for free-energy calculations

open access: yes, 2000
We have developed a new simulation algorithm for free-energy calculations. The method is a multidimensional extension of the replica-exchange method. While pairs of replicas with different temperatures are exchanged during the simulation in the original ...
Akio Kitao   +8 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Investigation of electrophysical, photo- and gas-sensitive properties of ZnO–SnO2 sol–gel films

open access: yesJournal of Advanced Dielectrics
Thin nanocomposite films based on tin dioxide with a low content of zinc oxide (0.5–5[Formula: see text]mol.%) were obtained by the sol–gel method. The synthesized films are 300–600[Formula: see text]nm thick and contains pore sizes of 19–29[Formula: see
Irina A. Gulyaeva   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Study of five-dimensional potential-energy surfaces for actinide isotopes by the macroscopic-microscopic method

open access: yesEPJ Web of Conferences, 2017
In this work, the nuclear potential-energy of the deformed nuclei as a function of shape coordinates is calculated in a five-dimensional (5D) parameter space of the axially symmetric generalized Lawrence shapes, on the basis of the macroscopic ...
Fan T.S.   +4 more
doaj   +1 more source

Potential Energy Distribution of Redundant Cable-Driven Robot Applied to Compliant Grippers: Method and Computational Analysis

open access: yesSensors, 2019
Cable-driven parallel robots with a redundant configuration have infinite solutions for their cable tension distribution to provide a specific wrench to the end-effector.
Alejandro Rodriguez-Barroso   +4 more
doaj   +1 more source

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