Results 101 to 110 of about 1,340,613 (267)

Reduction of Energy Consumption and GHGs Emission in Conventional Sand Casting Process by Application of a New CRIMSON Process [PDF]

open access: yes, 2012
In conventional foundry, engineers generally consider the quality of casting part as the most essential issue and regard the energy consumption and Green House Gas (GHGs) emission as the auxiliary ones.
Jolly, Mark R.   +4 more
core   +1 more source

An innovative deformation coordination method for analyzing distortion effects on box girders

open access: yesScientific Reports
A deformation coordination method is proposed in this study to account for the distortion effects on a box girder. The differential equation for distortion in vertical web box girders is derived based on the deformation coordination condition of the ...
Chenguang Wang   +7 more
doaj   +1 more source

Development of anti-twist mechanism for continuum manipulator and modeling focusing on bending stiffness

open access: yesNihon Kikai Gakkai ronbunshu, 2018
This paper proposes a new mechanism and a modeling method for continuum manipulators. The new mechanism is an anti-twist mechanism. Continuum manipulators have the merit of flexibility. However flexibility causes unexpected motions such as twisting under
Takaaki TOKUNAGA   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Methodologies for Assessment of Building's Energy Efficiency and Conservation: A Policy-Maker View [PDF]

open access: yes
Recent global peer-review reports have concluded on importance of buildings in tacking the energy security and climate change challenges. To integrate the buildings energy efficiency into the policy agenda, significant research efforts have been recently
Aleksandra Novikova
core  

Predicting ion diffusion from the shape of potential energy landscapes

open access: yes, 2023
We present an efficient method to compute diffusion coefficients of multi-particle systems with strong interactions directly from the geometry and topology of the potential energy field of the migrating particles.
Hannes, Gustafsson   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Boosting Australia’s energy productivity [PDF]

open access: yes, 2013
This report argues that Australia’s poor investment in energy efficiency is costing the nation tens of billions of dollars in economic growth.SummaryEnergy efficiency is both the single most costeffective way of lowering greenhouse gas emissions, and an ...
Olivia Kember
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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