Results 161 to 170 of about 2,577,081 (317)

Ultra-Fast Response ALTP Thermal Gas Flow Sensor Based on Si₃N₄/AlN Composite Insulating Structure. [PDF]

Micromachines (Basel)
Chen G, Chen X, Jin Z, Tian H, Zhao R, Tao B.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Electroosmosis and Solute Diffusion Transport of Maxwell Fluid Through a Polyelectrolyte-Grafted Microchannel with Modulated Charged Surfaces. [PDF]

Micromachines (Basel)
Shang Y, Li F, Yang C.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A three-dimensional linear analysis of steady ship motion in deep water

, 1986
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The investigation of steady ship motion in calm water is a classic problem in ship hydrodynamics, where ship waves and wave resistance are subjects of ...
Baar, J.M, Baar, Job
core  

Landscape Connectivity and Wildlife Access to Water Across an International Border: Barriers and Opportunities for Facilitating Transboundary Movement. [PDF]

Glob Chang Biol
Chivoiu B, Koen EL, Osland MJ, Gabler CA, Garrett JT, Reyes E, Bilodeau SA, Sternberg MA, Villarreal ML, Waller EK, Chambers SN, Benavides JA, Lawson RS, Martinez J.   +13 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Flow as a Non-Ordinary State of Consciousness: A Comparative Perspective with Awe, Meditation, and Psychedelic Experiences [PDF]

openThis thesis aims to explore flow as a non-ordinary state of consciousness (NOSC) that temporarily alters ordinary consciousness in non-pathological ways. Flow, also referred to as “optimal experience” in positive psychology by Mihaly Csikszentmihalyi,
DUMANLI, ELIF
core  

Assessing the unconventional reservoirs of the Nukhul formation in the Rudeis-Sidri Field, Gulf of Suez: petrophysical characterization and flow unit discrimination. [PDF]

Sci Rep
El-Sawy MZ, Nabawy BS, Shazly TF, Saleh AH.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source