Results 41 to 50 of about 2,577,081 (317)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Coupling between flexible ship and liquid sloshing using potential flow analysis

, 2010
The significant increase in demand for Liquefied Natural Gas (LNG) and the economic aspects of its transportation resulted in increases in the number and size of LNG carriers.
Temarel, Pandeli, Pandeli Temarel, Shihua Miao, Lee, Youngbum, Youngbum Lee, Miao, Shihua, Tan, Mingyi, Mingyi Tan   +7 more
core   +1 more source

Renal pericytes: regulators of medullary blood flow [PDF]

, 2012
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M., Kennedy-Lydon, T M, Wildman, S S P, Peppiatt-Wildman, C M, Peppiatt‐Wildman, C. M., Kennedy‐Lydon, T. M., Wildman, Scott S.P., Kennedy-Lydon, T. M., Crawford, C., Crawford, C, Wildman, S. S. P.   +10 more
core   +1 more source

Aerodynamic Design of a Laval Nozzle for Real Gas Using Hodograph Method

Aerospace, 2018
We propose an approach for the design of the subsonic part of plane and axisymmetric Laval nozzles for real gases. The proposed approach is based on the hodograph method and allows one to solve the inverse design problem directly.
Aleksandr Chikitkin, Mikhail Petrov, Roman Dushkov, Ernest Shifrin   +3 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Determination of the effective thickness of a porous electrode in a flow-through reactor; effect of the specific surface area of stainless steel fibres, used as a porous cathode during the deposition of Ag(I) ions.

, 2008
This study discusses the use of potential distribution analysis during the deposition of metal ions, at limiting current conditions and determines the optimum electrode thickness at which no hydrogen evolution occurs.
Nava Montes de Oca, José Luis, Ponce de León Albarrán, Carlos, Frías-Ferrer, A.J., Nava, J.L., Oropeza Guzmán, Mercedes T., González García, José, Oropeza, M.T., Ponce de León, C., González-García, J., Frías Ferrer, Ángel   +9 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

The Prediction of Hull Gesture and Flow Around Ship Based on Taylor Expansion Boundary Element Method

Polish Maritime Research, 2019
Based on the potential flow theory and traditional boundary element method (BEM), Taylor expansion boundary element method (TEBEM) is introduced in this paper for the prediction of the flow field around ship, as a result, hull gesture and pressure ...
Gong Jiaye, Li Yunbo
doaj   +1 more source

Investigation on seakeeping performance of an oil tanker on regular waves

Annals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2022
In this paper, investigation on seakeeping performance of an oil tanker on regular waves is presented. The numerical simulation was performed using a 3D diffrac-tion/radiation potential theory 3-D panel software.
Bianca Elena Roșca, Săndița Păcuraru
doaj   +1 more source