Results 101 to 110 of about 13,086,282 (240)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Composition of Potentials with Inner Functions.
Let \(B_ n\) be the unit ball in \(\mathbb{C}^ n\), \(n \geq 1\), \(S=\partial B_ n\). An inner function \(f\) on \(B_ n\) is said to be good if \[ \lim_{r \to 1} \int_ S \ln | f(rt) | d \sigma(t)=0, \] where \(\sigma\) is Haar's measure on \(S\). Let \(G_ \mu\) be the Green potential of regular Borel measure \(\mu\) on \(B_ 1\) satisfying \((1-| w |) \
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Bacterial Community Analysis and Potential Functions of Core Taxa in Different Parts of the Fungus Cantharellus cibarius [PDF]
WEI GE +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
We study the initial boundary value problem of an edge-degenerate wave equation. The operator $\Delta_{\mathbb{E}}$ with edge degeneracy on the boundary $\partial E$ was investigated in the literature.
Feida Jiang, Yue Luan, Gang Li
doaj
Equivalent Potential-Energy Functions
Many researchers have proposed their own potential-energy functions for the study of diatomic molecules, some of which have been proved to be equivalent. In this paper we suggest the application of a few simple rules to determine the equivalence between molecular potentials. The resulting systematic procedure is illustrated by means of several examples.
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

