Results 111 to 120 of about 4,745,445 (215)

Circular RNA profile in Graves' disease and potential function of hsa_circ_0090364. [PDF]

open access: yesEndocr Connect, 2022
Jiang Z   +7 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

External Glands of <i>Nepenthes</i> Traps: Structure and Potential Function. [PDF]

open access: yesInt J Mol Sci
Płachno BJ   +5 more
europepmc   +1 more source

The potential function and clinical application of FGF21 in metabolic diseases. [PDF]

open access: yesFront Pharmacol, 2022
Chen Z   +5 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Potential Function of Testicular MicroRNAs in Heat-Stress-Induced Spermatogenesis Disorders. [PDF]

open access: yesInt J Mol Sci, 2023
Gan M   +11 more
europepmc   +1 more source

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