Results 121 to 130 of about 4,979,212 (314)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Estimating Potential GDP for the Romanian Economy. An Eclectic Approach [PDF]

open access: yes
The paper provides potential output and output gap estimates for the Romanian economy in the period 1998-2008. Our approach consists in combining the production function structural method with several statistical de-trending methods.
Necula, Ciprian   +2 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Composition of Potentials with Inner Functions.

open access: yesMATHEMATICA SCANDINAVICA, 1992
Let \(B_ n\) be the unit ball in \(\mathbb{C}^ n\), \(n \geq 1\), \(S=\partial B_ n\). An inner function \(f\) on \(B_ n\) is said to be good if \[ \lim_{r \to 1} \int_ S \ln | f(rt) | d \sigma(t)=0, \] where \(\sigma\) is Haar's measure on \(S\). Let \(G_ \mu\) be the Green potential of regular Borel measure \(\mu\) on \(B_ 1\) satisfying \((1-| w |) \
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Application Potential of the Regulation of Tregs Function by Irisin in the Prevention and Treatment of Immune-Related Diseases [PDF]

open access: yes
Zhengjiang Wang,1,2,* Jiaqi Xu,1,2,* Liqun Mo,1 Renshu Zhan,1,2 Jin Zhang,3 Li Liu,1,2 Jun Jiang,4 Yingying Zhang,1,2 Yiping Bai1,2 1Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province ...
Jiang J   +8 more
core   +1 more source

Bacterial Community Analysis and Potential Functions of Core Taxa in Different Parts of the Fungus Cantharellus cibarius [PDF]

open access: yesPolish Journal of Microbiology, 2021
WEI GE   +5 more
doaj   +1 more source

Equilibrium Potentials and Additive Functionals [PDF]

open access: yesIndiana University Mathematics Journal, 1971
Duncan, Richard D., Getoor, R. K.
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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