Results 51 to 60 of about 16,411,473 (263)

Overview and future studies of potential hereditary effects of parental exposure to atomic bomb radiation on their offspring

Carcinogenesis
Abstract This is a brief review of studies conducted at the Atomic Bomb Casualty Commission and Radiation Effects Research Foundation regarding the possible transgenerational effects of atomic bomb radiation. These include clinical, epidemiological, and biological studies on birth defect, sex ratio, chromosome aberration, molecular ...
Nori Nakamura, Michiko Yamada, Ritsu Sakata, Waka Ohishi, Yoshimi Tatsukawa, Arikuni Uchimura   +5 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The exposure dose of reclaimed water in daily life: A mini review

Water Cycle, 2023
The exposure dose of reclaimed water is an important indicator to evaluate the potential risk of water reuse. This study summarized a general calculation model for the exposure dose of reclaimed water, taking into account the three exposure routes of ...
Liu He, De-Xiu Wu, Xin-Yang Zhang, Lu Peng   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

No evidence of increased mutations in the germline of a group of British nuclear test veterans

Scientific Reports, 2022
The potential germline effects of radiation exposure to military veterans present at British nuclear tests in Australia and the South Pacific is of considerable interest.
Alexander J. Moorhouse, Martin Scholze, Nicolas Sylvius, Clare Gillham, Christine Rake, Julian Peto, Rhona Anderson, Yuri E. Dubrova   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Influence of internal variability on population exposure to hydroclimatic changes

Environmental Research Letters, 2017
Future freshwater supply, human water demand, and people’s exposure to water stress are subject to multiple sources of uncertainty, including unknown future pathways of fossil fuel and water consumption, and ‘irreducible’ uncertainty arising from ...
Justin S Mankin, Daniel Viviroli, Mesfin M Mekonnen, Arjen Y Hoekstra, Radley M Horton, Jason E Smerdon, Noah S Diffenbaugh   +6 more
doaj   +1 more source

Increased population exposure to Amphan‐scale cyclones under future climates

Climate Resilience and Sustainability, 2022
Southern Asia experiences some of the most damaging climate events in the world, with loss of life from some cyclones in the hundreds of thousands. Despite this, research on climate extremes in the region is substantially lacking compared to other parts ...
Dann Mitchell, Laurence Hawker, James Savage, Rory Bingham, Natalie S. Lord, Md Jamal Uddin Khan, Paul Bates, Fabien Durand, Ahmadul Hassan, Saleemul Huq, Akm Saiful Islam, Yann Krien, Jeffrey Neal, Chris Sampson, Andy Smith, Laurent Testut   +15 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source