Results 121 to 130 of about 10,111,763 (293)

Behaviour of acoustic waves in a duct with Helmholtz resonator in presence of a temperature gradient [PDF]

open access: yes, 2014
Understanding the behaviour of one-dimensional acoustical wave propagation in ducts is very important for controlling combustion instabilities in propulsion, household burners, gas turbine combustors, and designing engineering mufflers.
Haydar , Aygun, Aygun, Haydar
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Gradient descent of the frame potential

open access: yes, 2009
Unit norm tight frames provide Parseval-like decompositions of vectors in terms of possibly nonorthogonal collections of unit norm vectors. One way to prove the existence of unit norm tight frames is to characterize them as the minimizers of a particular energy functional, dubbed the frame potential.
Casazza, Peter, Fickus, Matthew
openaire   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Wormholes generated by a density-gradient dependent equation of state in f(R,Lm,T) gravity

open access: yesPhysics Letters B
In this work, Static wormhole models are examined within the framework of curvature-based f(R,Lm,T) gravity theory. A relationship between the matter energy density and pressure is proposed for the Morris-Thorne wormhole geometry with a constant redshift
Sweeti Kiroriwal   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Habitat-associated rhizosphere microbiome differentiation in wild tea soils

open access: yesSpanish Journal of Soil Science
Low-disturbance wild tea plantations provide useful field systems for examining how natural habitat heterogeneity is associated with rhizosphere soil conditions and microbial community organization.
Yingyi Zhou   +4 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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