Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Dispositional hope as a potential outcome parameter among patients with advanced malignancy: An analysis of the ENABLE database. [PDF]
Cancer, 2022 Corn BW +4 more
europepmc +1 more source
Time line of potential predictive factors and outcome measures.
, 2015 Time line of potential predictive factors and outcome measures.
Eva Oernboel (758471) +5 more
core +1 more source
Estimation of Bounds on Potential Outcomes For Decision Making
, 2019 Estimation of individual treatment effects is commonly used as the basis for contextual decision making in fields such as healthcare, education, and economics. However, it is often sufficient for the decision maker to have estimates of upper and lower bounds on the potential outcomes of decision alternatives to assess risks and benefits.
Maggie Makar +3 more
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Estimating mean potential outcome under adaptive treatment length strategies in continuous time. [PDF]
Biometrics, 2022 Sun H, Ertefaie A, Johnson BA.
europepmc +1 more source
Glycosylated haemoglobin (HbA1c) and cortisol levels on admission to intensive care as predictors of outcome [PDF]
, 2009 Objective: To evaluate the predictive value of glycosylated haemoglobin and cortisol on admission, in critical care patients. Design: Prospective, observational, single centre study. Setting: 14 bedded Intensive care unit of a tertiary-level university
LaFerla, Godfrey +5 more
core
, 2011 The only reliable factors for assessing if a polymer-polymer click conjugation is successful are an assessment of the number average M̄n of the resulting molecular weight distribution (MWD) and the shape of the number, respectively, concentration ...
Preuss, C. M. +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Using the potential outcome framework to estimate optimal sample size for cluster randomized trials: a simulation-based algorithm. [PDF]
J Stat Comput Simul, 2021 Zhai R, Gutman R.
europepmc +1 more source