Results 81 to 90 of about 916,189 (263)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Estimating Potential Output and the Output Gap in Slovakia

open access: yesEastern European Economics, 2008
This paper estimates potential output and the output gap for Slovakia, which has enjoyed rapid growth with few signs of economic overheating in recent years. The paper applies two broad sets of approaches: conventional methods, represented by a statistical method and a production function approach; and a multivariate (MV) Kalman filter method.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Canada’s Potential Productivity and Output Growth: A Post-Crisis Assessment [PDF]

open access: yesInternational Productivity Monitor, 2010
This study investigates the impact of the current financial crisis on Canada’s potential GDP growth. Using a simple accounting framework to decompose trend GDP growth into changes in capital, labour services, and total factor productivity, we find a ...
Marcello Estevão, Evridiki Tsounta
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Performance and efficiency of national innovation systems: lessons from the wine industry

open access: yesWine Economics and Policy
The multiplicity of factors involved in the innovation process makes its measurement and evaluation a complex endeavor. In this study we propose a new approach to measure and decompose the efficiency of national innovation systems in the wine industry ...
Achille Amatucci   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Research on High-Precision and Wide-Range Spacecraft Potential Measurement Method Based on Capacitive Voltage Division

open access: yesSensors
The charging and discharging of satellite surfaces induced by the space plasma environment constitute a primary cause of spacecraft anomalies, particularly in geosynchronous orbits subject to geomagnetic substorms and hot plasma injections from the ...
Hong Yin   +8 more
doaj   +1 more source

DETERMINATION OF RESERVES FOR AGRICULTURAL PRODUCTION [PDF]

open access: yesEconomy and Sociology, 2016
The paper evidences the essence of land potential in agriculture as well as the methodology of determining the potential levels of land fertility during the production of different crop types based on an example of an existing agricultural enterprise ...
Tatiana DUDOGLO
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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