Results 91 to 100 of about 1,749,327 (291)
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
Frontiers in Pharmacology, 2019 Purpose: The aim of the present study was to develop and validate a Potentially Inappropriate Medications (PIM) list and alternative therapies for treatment of pain and inflammation in older people adapted to the Brazilian context.Methods: A preliminary ...
Fabiane Raquel Motter +3 more
doaj +1 more source
Prescribing Patterns of Potentially Inappropriate CNS-Active Medications in Older Adults
This cohort study examines prescribing patterns of potentially inappropriate central nervous system (CNS)–active medications among older adults with and without cognitive ...
Fendrick, A Mark +8 more
core +1 more source
Alternatives to potentially inappropriate medications for use in e-prescribing software: triggers and treatment algorithms [PDF]
, 2011 Objective: To describe the development of evidence-based electronic prescribing (e-prescribing) triggers and treatment algorithms for potentially inappropriate medications (PIMs) for older adults.
C. Eaton +9 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari +2 more
wiley +1 more source
Potentially inappropriate prescribing in children [PDF]
Family Practice, 2015 Emma, Barry, Susan M, Smith
openaire +2 more sources
Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors
British Journal of Clinical Pharmacology, EarlyView.Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem +5 more
wiley +1 more source
Trajectories of potentially inappropriate medication use among older adults in Saudi Arabia
Frontiers in PharmacologyBackgroundThe trajectories of potentially inappropriate medications (PIMs) among older adults have not been well studied. This study aims to determine the 3-year trajectories of PIM dispensation and their determinants in older adults in Saudi Arabia ...
Fouad F. Jabri +4 more
doaj +1 more source
Potentially suboptimal prescribing of medicines for older Aboriginal Australians in remote areas [PDF]
, 2019 Objectives: To investigate the prevalence of polypharmacy, under-prescribing and potentially inappropriate medicine use among Aboriginal Australians living in remote Western Australia. Design: Cross-sectional study.
Page, Amy +17 more
core +1 more source
Predictors of Potentially Inappropriate Stimulant Prescribing Among Adults
Pharmacoepidemiology and Drug SafetyABSTRACTPurposeIncreases in adult stimulant prescribing pose a potential risk due to the higher prevalence of contraindicated conditions among this population. We sought to identify patient, provider, and visit characteristics predictive of potentially inappropriate adult stimulant prescriptions.MethodsWe conducted a repeated cross‐sectional study ...
Pavan V. Thakkar +6 more
openaire +3 more sources