Results 71 to 80 of about 1,749,327 (291)

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Severe Headbanging Responsive to Levodopa in a Child With FOXP1 Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We report a 9‐year‐old female with FOXP1 syndrome due to a de novo in‐frame deletion in the FOXP1 gene. The child has a severe neurodevelopmental disorder including global developmental delay and autism spectrum disorder. At age 2, she developed severe headbanging, which was progressive and did not respond to multidisciplinary, behavioral ...
Pamela Veale, Christopher Tiessen, Vithya Gnanakumar   +2 more
wiley   +1 more source

A review on potentially inappropriate drug prescribing using beers criteria 2015 [PDF]

, 2020
ObjectiveTo review the literature of potentially inappropriate drug prescribing in elderly patients using Beers Criteria (BC) 2015FindingsKeywords including potentially inappropriate drug prescribing, Beers criteria 2015, elderly patients were used to ...
Bandi, Tejasree, Lanke, Sravani, Srinivas, Jakka Venkata, Sridhar, Srimath Tirumala Konduru   +3 more
core  

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

The Use of Unloader Bracing in the Management of Knee Osteoarthritis: A Modified Delphi Consensus Study

Arthroscopy, EarlyView.
Purpose To develop international expert consensus on the role of unloader bracing in the management of tibiofemoral osteoarthritis (OA) by addressing indications, contraindications, clinical evaluation, perioperative applications, and research priorities using a modified Delphi methodology.
Jonathan T. Super, Luke V. Tollefson, Iain R. Murray, Jorge Chahla, Andrew G. Geeslin, Darren L. Johnson, Ciara M. Stevenson, Robert F. LaPrade, Reykjavik Bracing Consensus Study Group, Robert F. LaPrade, Scott Anderson, Adam W. Anz, Sascha Beck, Andrew S. Bernhardson, Jorge Chahla, Anikar Chhabra, Mark E. Cinque, William M. Cregar, Pieter J. Emans, Scott C. Faucett, Andrew G. Geeslin, Darren L. Johnson, Tobias M. Jung, Patrick W. Kane, Nicholas I. Kennedy, Vickas Khanna, Cory A. Kwong, Christopher M. LaPrade, Martin Lind, Parth Lodhia, Gilbert Moatshe, Iain R. Murray, Johnathan Riboh, Anders Stalman, Ciara M. Stevenson, Wybren A. Van Der Wal, David Wasserstein, Daniel B. Whelan   +37 more
wiley   +1 more source

Potentially inappropriate prescribing in older adults in Mexico

Revista de Saúde Pública
OBJECTIVE To identify and quantify potentially inappropriate prescribing (prescripción potencialmente inapropiada, PPI) and other drug prescribing problems in public health care services in a population-based study at the three existing levels of ...
Pedro Jesús Saturno-Hernández, Ofelia Poblano-Verástegui, Omar Acosta-Ruiz, Arturo Cuauhtémoc Bautista-Morales, Patricia María Gómez-Cortez, José Luis Alcántara-Zamora, Luis Miguel Gutiérrez-Robledo   +6 more
doaj   +2 more sources

Potentially inappropriate prescribing in dementia: a state-of-the-art review since 2007

BMJ Open, 2020
Objectives Dementia frequently occurs alongside comorbidities. Coexisting conditions are often managed with multiple medications, leading to increased risk of potentially inappropriate medication and adverse drug reactions.
Kirsty Bowman, Linda Clare
doaj   +1 more source

A Pragmatic Trial of a Shared Decision‐Making Intervention to Improve Medication Adherence and Outcomes in Systemic Lupus Erythematosus: The HCQ‐SAFE Study

Arthritis &Rheumatology, EarlyView.
Objective Hydroxychloroquine (HCQ) nonadherence in systemic lupus erythematosus (SLE) stemming from decision complexities can be improved with shared decision‐making (SDM) tools clarifying benefits and harms. This study aimed to develop and evaluate HCQ‐SAFE, a pictogram‐based SDM tool during SLE visits.
Caroline Packee, Jay J. Patel, Jessica Kent, Betty Chewning, Sancia Ferguson, Patricia Tellez‐Giron, David Gazeley, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

Prevalence and Predictors of Potentially Inappropriate Medications Among Patients Aged ≥65 Years on Hospital Admissions in Kuwait

Clinical Interventions in Aging, 2022
Hesah Alshammari, Eman Al-Saeed, Zamzam Ahmed, Zoe Aslanpour Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UKCorrespondence: Hesah Alshammari, Department of Clinical and ...
Alshammari H, Al-Saeed E, Ahmed Z, Aslanpour Z   +3 more
doaj  

Potentially inappropriate prescribing in older patients discharged from acute care hospitals to residential aged care facilities [PDF]

, 2014
Background: The frequency of prescribing potentially inappropriate medications (PIMs) in older patients remains high despite evidence of adverse outcomes from their use.
Nissen, Lisa, Mitchell, Charles, Gray, Len C., Poudel, Arjun, Hubbard, Ruth E., Peel, Nancye M.   +5 more
core   +1 more source